Nettle (Urtica Dioica L.) Modulates Angiogenesis by Targeting the PI3K/AKT/eNOS Pathway in Prostate Cancer

Nettle (Urtica Dioica L.) Modulates Angiogenesis by Targeting the PI3K/AKT/eNOS Pathway in Prostate Cancer

Background: Medicinal plants, predominantly those rich in polyphenolic mixtures, have been recommended to have chemopreventive and chemotherapeutic effects. This study aimed to investigate the effects of Urtica dioica L. extract (UDE) on angiogenesis and prostate cancer (PCa) cell progression throug...

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Bibliographic Details
Main Authors: Abduladheem AL-Attabi, Mohammed Sabah Mohammed, Noor Ali Yazi AL-Khazali, Sami Awad Alkubaisy, Muna S. Merza, Mohanad Ali Abdulhadi, Yasser Fakri Mustafa
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-07-01
Series:Middle East Journal of Cancer
Subjects:
prostatic neoplasms
urtica dioica
angiogenesis
vegf
pi3k/akt/enos pathway
Online Access:https://mejc.sums.ac.ir/article_50506_64cedae82e41f36956eeb9ca25ce4436.pdf
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