Messenger RNA (mRNA) based therapeutics in transforming cardiovascular care: Progress, regulatory challenges and future perspectives

Messenger RNA (mRNA) based therapeutics in transforming cardiovascular care: Progress, regulatory challenges and future perspectives

Messenger RNA (mRNA) is emerging as a new tool for therapeutic intervention, providing a transient, programmable platform for the treatment of complex diseases. Unlike DNA-based therapies, mRNA does not integrate into the genome and is considered more safe. The success of mRNA vaccines, combined wit...

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Bibliographic Details
Main Authors: Mudassir Khan, Umberto M. Musazzi, Sara Manellari, Nayla Mouawad, Giulia Damiano, Raffaella Rinaldi, Angela Raucci, Sarah Costantino, Francesco Paneni, Paola Minghetti, Giulio Pompilio, Maria Cristina Vinci
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Pharmacological Research
Subjects:
mRNA-based therapeutics
Cardiovascular diseases (CVD)
mRNA delivery systems
Regenerative medicine
Regulatory affairs
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825002725
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