Clinical and Radiographic Outcomes of Autologous Platelet-Rich Products in Regenerative Endodontics: A Systematic Review and Meta-Analysis

QR Code

Clinical and Radiographic Outcomes of Autologous Platelet-Rich Products in Regenerative Endodontics: A Systematic Review and Meta-Analysis

<b>Background:</b> Regenerative endodontic therapy (RET) allows for continued root development in necrotic immature permanent teeth. Autologous platelet concentrates (APC) such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are proposed alternatives to conventional blood cl...

Full description

Saved in:

Bibliographic Details
Main Authors:	Raewyn Huang, Wei Chen, Matthew Fang, Ove A. Peters, Sepanta Hosseinpour
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Series:	Dentistry Journal
Subjects:	autologous platelet concentrates platelet-rich plasma platelet-rich fibrin immature teeth regenerative endodontic therapy
Online Access:	https://www.mdpi.com/2304-6767/13/6/236
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin–mediated regenerative endodontic procedures in teeth with periapical pathology: a CBCT study
by: Swati Markandey, et al.
Published: (2022-11-01)

Comparative Analysis of Regenerative Endodontic Procedures with Different Scaffold Materials
by: Sherif El Sayed Sultan, et al.
Published: (2025-06-01)

Comparative Evaluation of Advanced Platelet-Rich Fibrin and Blood Clot as Scaffolds in Regenerative Endodontics for Immature Necrotic Teeth: A Randomized Clinical Study
by: Seema Qamar, et al.
Published: (2025-06-01)

A Randomized Controlled Study Comparing Albumin-Enriched Platelet-Rich Fibrin and Conventional Platelet-Rich Fibrin for the Treatment of Intrabony Defects
by: Sharmila Kumari, et al.
Published: (2025-06-01)

PROSPECTS FOR THE DEVELOPMENT OF REGENERATIVE TECHNOLOGIES. CURRENT KNOWLEDGE OF PLATELET RICH PLASMA AND THE POSSIBILITY OF ITS APPLICATION IN TREATMENT OF COMPLICATED UROLOGICAL DESEASES
by: V. L. MEDVEDEV, et al.
Published: (2018-07-01)

Leukocyte platelet-rich fibrin in endodontic microsurgery: a report of 2 cases
by: Mariana Domingos Pires, et al.
Published: (2022-05-01)

Injection of platelet aggregates in facial rejuvenation: a systematic review
by: Carmen Lucia Mueller Storrer, et al.
Published: (2019-06-01)

Contingent Analysis of Open Flap Debridement, Leukocyte-Rich Platelet-Rich Fibrin and Titanium Platelet-Rich Fibrin in the Treatment of Three-Walled Intra-Bony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Study
by: Gowri Pendyala, et al.
Published: (2025-01-01)

The histological and radiological evaluation of autologous peripheral venous blood concentrates in socket preservation: a systematic review and meta-analysis
by: Yusheng Meng, et al.
Published: (2025-07-01)

The use of platelet-rich plasma (PRP) in urology
by: S. V. Popov, et al.
Published: (2023-04-01)

A bibliometric analysis of the global status of platelet-rich plasma in regenerative medicine from 2004 to 2023
by: Siwen Zhang, et al.
Published: (2025-12-01)

Optimization of Platelet-Rich Plasma Preparation for Use in Clinical Practice
by: K. I. Burykin, et al.
Published: (2023-07-01)

Molecular and Cellular Aspects of Socket Healing in the Absence and Presence of Graft Materials and Autologous Platelet Concentrates: a Focused Review
by: Pedro de Sousa Gomes, et al.
Published: (2019-09-01)

Radiographic Evaluation in Alveolar Preservation Using Platelet-Rich Fibrin: A Randomized Controlled Trial
by: Magdalena Molina-Barahona, et al.
Published: (2025-05-01)

Wound Healing in Diabetic Foot Ulcer Patients Using Combined Use of Platelet Rich Fibrin and Hyaluronic Acid, Platelet Rich Fibrin and Placebo: An Open Label, Randomized Controlled Trial
by: Ronald Winardi Kartika, et al.
Published: (2021-10-01)

Evaluation of Osteocalcin Level in Gingival Crevicular Fluid in Periodontal Intrabony Defects Treated with Autologous Platelet Rich Fibrin: Non-Randomized Experimental Study
by: Sahana Srinivas, et al.
Published: (2024-12-01)

Evaluation of Peri-apical Healing in Patients of Apical Periodontitis with Mature Necrotic Teeth Treated using A-PRF+versus i-PRF: A Research Protocol
by: Tejas Suryawanshi, et al.
Published: (2025-06-01)

Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases
by: I. A. Filatova, et al.
Published: (2022-01-01)

Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
by: A. Yu. Vaza, et al.
Published: (2016-06-01)

Comparison of 20% Autologous Platelet-Rich Plasma Versus Conventional Treatment in Moderate to Severe Dry Eye Patients
by: Shubhi Sachan, et al.
Published: (2025-06-01)

Histological Evaluation of Local Application of Peripheral Blood Mesenchymal Stem Cells and Platelet-Rich Fibrin Matrix on Bone Healing of Rats
by: Rasim Mahdi Salih, et al.
Published: (2025-04-01)

Local administration of autologous platelet-rich plasma in a female patient with skin ulcer defect
by: S M Noskov, et al.
Published: (2011-02-01)

Pathomorphological features of eyelid tissue scarring after treatment with platelet-rich plasma
by: I. A. Filatova, et al.
Published: (2022-12-01)

Mechanisms of the therapeutic effect of platelet-rich plasma in macular hole surgery
by: N. S. Demchenko, et al.
Published: (2023-03-01)

Use of Platelet-Rich Fibrin for Jaw Osteonecrosis: A Case Report
by: Petya Kanazirska, et al.
Published: (2020-12-01)

Optimization of Platelet-Rich Plasma Fraction Selection for Surgical Treatment of Macular Holes
by: V. N. Kazaykin, et al.
Published: (2023-12-01)

Collagen membrane versus platelet rich fibrin membrane in bone graft healing: An experimental study in sheep.
by: Mahdi O. Abdullah, et al.
Published: (2020-12-01)

Prospects for use of platelet-rich plasma in the treatment of rheumatoid arthritis
by: S. V. Maglevaniy, et al.
Published: (2021-02-01)

The Effect of Thymoquinone and Platelet-Rich Plasma on Intra-Abdominal Adhesions
by: Gökhan Karaca, et al.
Published: (2025-06-01)

Clinical and radiographic outcomes of regenerative endodontic treatment performed by endodontic postgraduate students: a retrospective study
by: Hadi Rajeh Alfahadi, et al.
Published: (2022-05-01)

Alveolar Ridge Preservation after Tooth Extraction Using Different Bone Graft Materials and Autologous Platelet Concentrates: a Systematic Review
by: Arturas Stumbras, et al.
Published: (2019-03-01)

Letter to the Editor, “Platelet-Rich Fibrin as a Novel Bio-Carrier for the Transfer of Antibiotics to the Root Canal System”
by: Rojin Samani, et al.
Published: (2025-07-01)

Current regenerative approaches to the treatment of generalized periodontitis in young people (literature review)
by: O.V Kopchak, et al.
Published: (2024-04-01)

Effect of platelet rich fibrin on post-operative sequelae following mandibular third molar surgery a prospective comparative study
by: Chayan Kumar Kundu, et al.
Published: (2024-11-01)

Regenerative Synergy: Combining Platelet-rich Plasma with Transcutaneous Temperature-controlled Radiofrequency for Enhanced Treatment of Stress Urinary Incontinence in Peri- and Postmenopausal Women
by: Smit Bharat Solanki
Published: (2025-04-01)

Gene Expression Modulation in Bovine Endometrial Cells Infected with Gammaherpesvirus Type 4 and Exposed to Lipopolysaccharide in the Presence of Platelet-Rich Plasma
by: Sofía López, et al.
Published: (2025-05-01)

Pulp revascularization with and without platelet-rich plasma in two anterior teeth with horizontal radicular fractures: a case report
by: Edison Arango-Gómez, et al.
Published: (2019-11-01)

Synergistic effect of photobiomodulation and leukocyte-platelet rich fibrin on bone regeneration in rat critical defects
by: Ali Sadeghian, et al.
Published: (2025-08-01)

Available methods to enhance regenerative potential of plastic materials for bone defects replacement in orthopedics. Part 1. Autologous platelet rich plasma
by: A. M. Fayn, et al.
Published: (2022-03-01)

Assessment of Platelet-Rich Fibrin (PRF) in Enhancing Periodontal Regeneration
by: Fatema Akhter
Published: (2025-06-01)