Establishment of a human induced pluripotent stem cell line from a patient with Alagille syndrome carrying heterozygous mutation in JAG1 gene

Alagille syndrome (ALGS) is a complex rare genetic disorder that involves multiple organ systems. We established an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells of a one-year-old boy with Alagille syndrome carrying a heterozygous mutation c.234C > A (p.C78X) i...

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Главные авторы: Bin Wang, Wei Song
Формат: Статья
Язык:английский
Опубликовано: Elsevier 2025-09-01
Серии:Stem Cell Research
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1873506125001382
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