The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
The presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis a...
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Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
2024-01-01
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Series: | Неотложная медицинская помощь |
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Online Access: | https://www.jnmp.ru/jour/article/view/1727 |
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author | A. V. Prirodov S. V. Zhuravel E. Yu. Bakharev I. I. Goncharova P. D. Zorin E. V. Klychnikova E. V. Tazina A. A. Grin S. S. Petrikov |
author_facet | A. V. Prirodov S. V. Zhuravel E. Yu. Bakharev I. I. Goncharova P. D. Zorin E. V. Klychnikova E. V. Tazina A. A. Grin S. S. Petrikov |
author_sort | A. V. Prirodov |
collection | DOAJ |
description | The presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis are described, experimental and clinical data on the disruption of the production of the endothelial relaxing factor in subarachnoid hemorrhage are presented. |
format | Article |
id | doaj-art-db977b65c52b42cb9ce4a502bf53418c |
institution | Matheson Library |
issn | 2223-9022 2541-8017 |
language | Russian |
publishDate | 2024-01-01 |
publisher | Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department |
record_format | Article |
series | Неотложная медицинская помощь |
spelling | doaj-art-db977b65c52b42cb9ce4a502bf53418c2025-08-04T10:30:25ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172024-01-0112463764910.23934/2223-9022-2023-12-4-637-649902The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral AneurysmsA. V. Prirodov0S. V. Zhuravel1E. Yu. Bakharev2I. I. Goncharova3P. D. Zorin4E. V. Klychnikova5E. V. Tazina6A. A. Grin7S. S. Petrikov8N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University; A.I. Yevdokimov Moscow State University of Medicine and DentistryN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and DentistryThe presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis are described, experimental and clinical data on the disruption of the production of the endothelial relaxing factor in subarachnoid hemorrhage are presented.https://www.jnmp.ru/jour/article/view/1727angiospasmvascular spasmsahnitrogen monoxidecerebral aneurysminhalation |
spellingShingle | A. V. Prirodov S. V. Zhuravel E. Yu. Bakharev I. I. Goncharova P. D. Zorin E. V. Klychnikova E. V. Tazina A. A. Grin S. S. Petrikov The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms Неотложная медицинская помощь angiospasm vascular spasm sah nitrogen monoxide cerebral aneurysm inhalation |
title | The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms |
title_full | The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms |
title_fullStr | The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms |
title_full_unstemmed | The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms |
title_short | The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms |
title_sort | role of nitric oxide in the autoregulation of cerebral blood flow and the pathogenesis of cerebral vascular spasm in patients with ruptured cerebral aneurysms |
topic | angiospasm vascular spasm sah nitrogen monoxide cerebral aneurysm inhalation |
url | https://www.jnmp.ru/jour/article/view/1727 |
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