The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms

The presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis a...

Full description

Saved in:
Bibliographic Details
Main Authors: A. V. Prirodov, S. V. Zhuravel, E. Yu. Bakharev, I. I. Goncharova, P. D. Zorin, E. V. Klychnikova, E. V. Tazina, A. A. Grin, S. S. Petrikov
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2024-01-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/1727
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839579971568271360
author A. V. Prirodov
S. V. Zhuravel
E. Yu. Bakharev
I. I. Goncharova
P. D. Zorin
E. V. Klychnikova
E. V. Tazina
A. A. Grin
S. S. Petrikov
author_facet A. V. Prirodov
S. V. Zhuravel
E. Yu. Bakharev
I. I. Goncharova
P. D. Zorin
E. V. Klychnikova
E. V. Tazina
A. A. Grin
S. S. Petrikov
author_sort A. V. Prirodov
collection DOAJ
description The presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis are described, experimental and clinical data on the disruption of the production of the endothelial relaxing factor in subarachnoid hemorrhage are presented.
format Article
id doaj-art-db977b65c52b42cb9ce4a502bf53418c
institution Matheson Library
issn 2223-9022
2541-8017
language Russian
publishDate 2024-01-01
publisher Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
record_format Article
series Неотложная медицинская помощь
spelling doaj-art-db977b65c52b42cb9ce4a502bf53418c2025-08-04T10:30:25ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172024-01-0112463764910.23934/2223-9022-2023-12-4-637-649902The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral AneurysmsA. V. Prirodov0S. V. Zhuravel1E. Yu. Bakharev2I. I. Goncharova3P. D. Zorin4E. V. Klychnikova5E. V. Tazina6A. A. Grin7S. S. Petrikov8N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University; A.I. Yevdokimov Moscow State University of Medicine and DentistryN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and DentistryThe presented literature review is devoted to the role of the endothelial relaxing factor – nitric oxide (NO) – in the regulation of cerebral blood flow in patients with ruptured intracranial aneurysms. Modern views on the physiology of NO, methods of regulation and autoregulation of its synthesis are described, experimental and clinical data on the disruption of the production of the endothelial relaxing factor in subarachnoid hemorrhage are presented.https://www.jnmp.ru/jour/article/view/1727angiospasmvascular spasmsahnitrogen monoxidecerebral aneurysminhalation
spellingShingle A. V. Prirodov
S. V. Zhuravel
E. Yu. Bakharev
I. I. Goncharova
P. D. Zorin
E. V. Klychnikova
E. V. Tazina
A. A. Grin
S. S. Petrikov
The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
Неотложная медицинская помощь
angiospasm
vascular spasm
sah
nitrogen monoxide
cerebral aneurysm
inhalation
title The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
title_full The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
title_fullStr The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
title_full_unstemmed The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
title_short The Role of Nitric Oxide in the Autoregulation of Cerebral Blood Flow and the Pathogenesis of Cerebral Vascular Spasm in Patients with Ruptured Cerebral Aneurysms
title_sort role of nitric oxide in the autoregulation of cerebral blood flow and the pathogenesis of cerebral vascular spasm in patients with ruptured cerebral aneurysms
topic angiospasm
vascular spasm
sah
nitrogen monoxide
cerebral aneurysm
inhalation
url https://www.jnmp.ru/jour/article/view/1727
work_keys_str_mv AT avprirodov theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT svzhuravel theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT eyubakharev theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT iigoncharova theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT pdzorin theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT evklychnikova theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT evtazina theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT aagrin theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT sspetrikov theroleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT avprirodov roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT svzhuravel roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT eyubakharev roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT iigoncharova roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT pdzorin roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT evklychnikova roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT evtazina roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT aagrin roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms
AT sspetrikov roleofnitricoxideintheautoregulationofcerebralbloodflowandthepathogenesisofcerebralvascularspasminpatientswithrupturedcerebralaneurysms