Molecular mechanism of neurodegeneration in spinal muscular atrophy
In the last decade, pathogenetic methods for the treatment of spinal muscular atrophy 5q have been developed. These include increased expression of the SMN2 gene, correction of SMN2 splicing, or reexpression of the SMN1 gene. Despite the comprehension of the genetic causes of the disease and the exi...
Saved in:
Main Authors: | A. I. Vlasenko, V. D. Nazarov, S. V. Lapin, A. V. Mazing, E. A. Surkova, T. V. Blinova, M. P. Topuzova, T. M. Alekseeva |
---|---|
Format: | Article |
Language: | Russian |
Published: |
ABV-press
2024-09-01
|
Series: | Нервно-мышечные болезни |
Subjects: | |
Online Access: | https://nmb.abvpress.ru/jour/article/view/621 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Quantitative and structural features of the SMN1 and SMN2 genes in patients with spinal muscular atrophy 5q
by: A. I. Vlasenko, et al.
Published: (2024-12-01) -
Factors modifying the course of spinal muscular atrophy 5q
by: M. A. Akhkiamova, et al.
Published: (2024-01-01) -
Characteristics of genetic changes in the <i>SMN1</i> gene in spinal muscular atrophy 5q
by: A. V. Dil, et al.
Published: (2022-09-01) -
Adult spinal muscular atrophy: problems of early diagnosis
by: Yu. A. Shpilyukova, et al.
Published: (2022-12-01) -
Diagnostic criteria for spinal muscular atrophy 5q
by: I. V. Sharkova, et al.
Published: (2021-12-01)