FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS
Purpose: to study methods of prophylaxis of venous thromboembolism (VTE) in oncologic patients.Materials and methods: results of treatment of 92 patients with various options of an abdominal cancer were analysed. 43 patients (I group) received low-molecular-weight heparin (LMWH) as agent of anticoag...
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2014-12-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/12 |
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| author | I. I. Katelnitskyy O. I. Kit O. V. Katelnitskaya I. I. Prostov A. V. Ivashenko K. A. Tumanova |
| author_facet | I. I. Katelnitskyy O. I. Kit O. V. Katelnitskaya I. I. Prostov A. V. Ivashenko K. A. Tumanova |
| author_sort | I. I. Katelnitskyy |
| collection | DOAJ |
| description | Purpose: to study methods of prophylaxis of venous thromboembolism (VTE) in oncologic patients.Materials and methods: results of treatment of 92 patients with various options of an abdominal cancer were analysed. 43 patients (I group) received low-molecular-weight heparin (LMWH) as agent of anticoagulant prevention (enoxaparin 40 mg subcutaneuosly per day for 10 days). The 2nd group was presented by 49 patients, not received anticoagulant therapy. Coagulation profiles, D-dimers and liver function tests were studied.Results: in I group popliteal vein thrombosis was revealed in 2 (4,7%) cases. In two patients (4,7%) varicothromboflebitis was revealed. In 2nd group femoropopliteal thrombosis was diagnosed in 5 patients (10,2%) and thrombosis of superficial veins of lower extremities in 3 patients (6,1%).Summary: it is more preferable to use LMWH for prevention of VTE. An adequate laboratory control in such patients and selection of an individual dose depends on results of APTT (activated partial thromboplastin time). Especially it concerns to patients with metastatic liver cancer and another groups of high-risk cancer patients. |
| format | Article |
| id | doaj-art-db5e8c8cd8ef460c969f01ea231ee044 |
| institution | Matheson Library |
| issn | 2219-8075 2618-7876 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj-art-db5e8c8cd8ef460c969f01ea231ee0442025-07-03T16:13:37ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762014-12-0104545710.21886/2219-8075-2014-4-54-5711FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTSI. I. Katelnitskyy0O. I. Kit1O. V. Katelnitskaya2I. I. Prostov3A. V. Ivashenko4K. A. Tumanova5Rostov State Medical UniversityRostov oncological research instituteRostov oncological research instituteRostov State Medical UniversityRostov Railway HospitalRostov oncological research institutePurpose: to study methods of prophylaxis of venous thromboembolism (VTE) in oncologic patients.Materials and methods: results of treatment of 92 patients with various options of an abdominal cancer were analysed. 43 patients (I group) received low-molecular-weight heparin (LMWH) as agent of anticoagulant prevention (enoxaparin 40 mg subcutaneuosly per day for 10 days). The 2nd group was presented by 49 patients, not received anticoagulant therapy. Coagulation profiles, D-dimers and liver function tests were studied.Results: in I group popliteal vein thrombosis was revealed in 2 (4,7%) cases. In two patients (4,7%) varicothromboflebitis was revealed. In 2nd group femoropopliteal thrombosis was diagnosed in 5 patients (10,2%) and thrombosis of superficial veins of lower extremities in 3 patients (6,1%).Summary: it is more preferable to use LMWH for prevention of VTE. An adequate laboratory control in such patients and selection of an individual dose depends on results of APTT (activated partial thromboplastin time). Especially it concerns to patients with metastatic liver cancer and another groups of high-risk cancer patients.https://www.medicalherald.ru/jour/article/view/12oncologic patientsvenous thromboembolismanticoagulant therapy |
| spellingShingle | I. I. Katelnitskyy O. I. Kit O. V. Katelnitskaya I. I. Prostov A. V. Ivashenko K. A. Tumanova FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS Медицинский вестник Юга России oncologic patients venous thromboembolism anticoagulant therapy |
| title | FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS |
| title_full | FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS |
| title_fullStr | FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS |
| title_full_unstemmed | FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS |
| title_short | FEATURES OF PROPHYLAXIS OF POSTOPERATIVE VENOUS THROMBOEMBOLISM IN ONCOLOGIC PATIENTS |
| title_sort | features of prophylaxis of postoperative venous thromboembolism in oncologic patients |
| topic | oncologic patients venous thromboembolism anticoagulant therapy |
| url | https://www.medicalherald.ru/jour/article/view/12 |
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