Antibacterial activity of probiotics in bladder tumor patients.

The chronic urinary tract infection (UTI) is a risk  factor that worsens a natural course of bladder tumors. Using of probiotics, possessing antagonistic influence on pathogenic microflora and immunocorrection effect, for preventive maintenance and treat­ment of a chronic UTI in bladder tumor patien...

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Main Author: R. N. Molchanov
Format: Article
Language:English
Published: Dnipro State Medical University 2014-09-01
Series:Medičnì Perspektivi
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Online Access:https://journals.uran.ua/index.php/2307-0404/article/view/30395
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author R. N. Molchanov
author_facet R. N. Molchanov
author_sort R. N. Molchanov
collection DOAJ
description The chronic urinary tract infection (UTI) is a risk  factor that worsens a natural course of bladder tumors. Using of probiotics, possessing antagonistic influence on pathogenic microflora and immunocorrection effect, for preventive maintenance and treat­ment of a chronic UTI in bladder tumor patients is an actual and perspective direction. The goal of the  research was studying antimicrobial  and anti-inflammatory effect  of  a  single bladder instillation of either lactobacilli or aerococci in bladder tumor patients. In the preoperative period a single  bladder instillation with either lactobacterin or a-bacterin preparation to 35 bladder tumor patients was done. Bacteriuria, leucocyturia, lactobacilli and aerococci count in  urine were measured before and in 1, 3, 6 and 24 hours after instillation. Decrease in bacteriuria level in both groups of patients was revealed. Lactobacilli and aerococci count in  urine gradually decreased up to complete elimination in 24 hours (in 1 patient who received lactobacterin (12,5 %) and in 9 patients who received a-bacterin. (40,9 %). Leucocyturia study did not show statistically confidence dynamics throughout the observation period in both groups. Thus, bladder instillation with lactobacterin or a-bacterin leads to suppression of uropathogenic microflora in bladder tumor patients; in the majority of patients spontaneous elimination of lactobacilli and aerococci occurs within 24 hours.
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spelling doaj-art-db0a43e8d3044775b4760683892cdefe2025-06-27T10:23:49ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042786-48042014-09-0119310.26641/2307-0404.2014.3.30395Antibacterial activity of probiotics in bladder tumor patients.R. N. MolchanovThe chronic urinary tract infection (UTI) is a risk  factor that worsens a natural course of bladder tumors. Using of probiotics, possessing antagonistic influence on pathogenic microflora and immunocorrection effect, for preventive maintenance and treat­ment of a chronic UTI in bladder tumor patients is an actual and perspective direction. The goal of the  research was studying antimicrobial  and anti-inflammatory effect  of  a  single bladder instillation of either lactobacilli or aerococci in bladder tumor patients. In the preoperative period a single  bladder instillation with either lactobacterin or a-bacterin preparation to 35 bladder tumor patients was done. Bacteriuria, leucocyturia, lactobacilli and aerococci count in  urine were measured before and in 1, 3, 6 and 24 hours after instillation. Decrease in bacteriuria level in both groups of patients was revealed. Lactobacilli and aerococci count in  urine gradually decreased up to complete elimination in 24 hours (in 1 patient who received lactobacterin (12,5 %) and in 9 patients who received a-bacterin. (40,9 %). Leucocyturia study did not show statistically confidence dynamics throughout the observation period in both groups. Thus, bladder instillation with lactobacterin or a-bacterin leads to suppression of uropathogenic microflora in bladder tumor patients; in the majority of patients spontaneous elimination of lactobacilli and aerococci occurs within 24 hours.https://journals.uran.ua/index.php/2307-0404/article/view/30395tumorurinary bladderprobioticurinary tract infection
spellingShingle R. N. Molchanov
Antibacterial activity of probiotics in bladder tumor patients.
Medičnì Perspektivi
tumor
urinary bladder
probiotic
urinary tract infection
title Antibacterial activity of probiotics in bladder tumor patients.
title_full Antibacterial activity of probiotics in bladder tumor patients.
title_fullStr Antibacterial activity of probiotics in bladder tumor patients.
title_full_unstemmed Antibacterial activity of probiotics in bladder tumor patients.
title_short Antibacterial activity of probiotics in bladder tumor patients.
title_sort antibacterial activity of probiotics in bladder tumor patients
topic tumor
urinary bladder
probiotic
urinary tract infection
url https://journals.uran.ua/index.php/2307-0404/article/view/30395
work_keys_str_mv AT rnmolchanov antibacterialactivityofprobioticsinbladdertumorpatients