EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS
Results of research of efficacy and tolerability of lamitor (lamotrigine) in the treatment of idiopathic focal and generalized forms of epilepsy as monotherapy or in polytherapy in children and adolescents are presented. 25 patients were included in our research, aged from 2 till 18 years, with idio...
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ABV-press
2015-06-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/66 |
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| author | K. Yu. Mukhin O. A. Pylaeva M. B. Mironov |
| author_facet | K. Yu. Mukhin O. A. Pylaeva M. B. Mironov |
| author_sort | K. Yu. Mukhin |
| collection | DOAJ |
| description | Results of research of efficacy and tolerability of lamitor (lamotrigine) in the treatment of idiopathic focal and generalized forms of epilepsy as monotherapy or in polytherapy in children and adolescents are presented. 25 patients were included in our research, aged from 2 till 18 years, with idiopathic focal (n=10) and generalized (n=15) epilepsy, which received lamitor in monotherapy (5 patients) or in polytherapy (20 patients). As a whole, remission was reached at 18 of 25 patients (72%), significant improvement – at 5 of 25 (20%), the effect was absent – 1 patient (4%), deterioration was noted only in 1 case (4%). Efficiency of lamitor in dependence on epilepsy form was considered. Good tolerability of lamitor is noted. Thus, our research demonstrated high efficiency and good tolerability of lamitor as an additional antiepileptic drug and in monotherapy in the treatment of idiopathic epilepsies in children and adolescents. |
| format | Article |
| id | doaj-art-db09191099e34bcc9a2efc2421a1ad11 |
| institution | Matheson Library |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| publishDate | 2015-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj-art-db09191099e34bcc9a2efc2421a1ad112025-08-04T14:12:11ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782015-06-018131210.17650/2073-8803-2013-8-1-3-1259EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTSK. Yu. Mukhin0O. A. Pylaeva1M. B. Mironov2Институт детской неврологии и эпилепсии им. Святителя Луки Ê.Yu. Mukhin, Î.À. Pylaeva, Ì.B.Институт детской неврологии и эпилепсии им. Святителя ЛукиИнститут детской неврологии и эпилепсии им. Святителя ЛукиResults of research of efficacy and tolerability of lamitor (lamotrigine) in the treatment of idiopathic focal and generalized forms of epilepsy as monotherapy or in polytherapy in children and adolescents are presented. 25 patients were included in our research, aged from 2 till 18 years, with idiopathic focal (n=10) and generalized (n=15) epilepsy, which received lamitor in monotherapy (5 patients) or in polytherapy (20 patients). As a whole, remission was reached at 18 of 25 patients (72%), significant improvement – at 5 of 25 (20%), the effect was absent – 1 patient (4%), deterioration was noted only in 1 case (4%). Efficiency of lamitor in dependence on epilepsy form was considered. Good tolerability of lamitor is noted. Thus, our research demonstrated high efficiency and good tolerability of lamitor as an additional antiepileptic drug and in monotherapy in the treatment of idiopathic epilepsies in children and adolescents.https://rjdn.abvpress.ru/jour/article/view/66epilepsyidiopathic focal epilepsyidiopathic generalized epilepsylamotrigineefficacytolerabilityin children and adolescents |
| spellingShingle | K. Yu. Mukhin O. A. Pylaeva M. B. Mironov EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS Русский журнал детской неврологии epilepsy idiopathic focal epilepsy idiopathic generalized epilepsy lamotrigine efficacy tolerability in children and adolescents |
| title | EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS |
| title_full | EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS |
| title_fullStr | EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS |
| title_full_unstemmed | EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS |
| title_short | EFFICACY AND TOLERABILITY OF LAMITOR (LAMOTRIGINE) IN THE TREATMENT OF IDIOPATHIC FOCAL AND GENERALIZED EPILEPSY IN MONOTHERAPY AND IN POLYTHERAPY IN CHILDREN AND ADOLESCENTS |
| title_sort | efficacy and tolerability of lamitor lamotrigine in the treatment of idiopathic focal and generalized epilepsy in monotherapy and in polytherapy in children and adolescents |
| topic | epilepsy idiopathic focal epilepsy idiopathic generalized epilepsy lamotrigine efficacy tolerability in children and adolescents |
| url | https://rjdn.abvpress.ru/jour/article/view/66 |
| work_keys_str_mv | AT kyumukhin efficacyandtolerabilityoflamitorlamotrigineinthetreatmentofidiopathicfocalandgeneralizedepilepsyinmonotherapyandinpolytherapyinchildrenandadolescents AT oapylaeva efficacyandtolerabilityoflamitorlamotrigineinthetreatmentofidiopathicfocalandgeneralizedepilepsyinmonotherapyandinpolytherapyinchildrenandadolescents AT mbmironov efficacyandtolerabilityoflamitorlamotrigineinthetreatmentofidiopathicfocalandgeneralizedepilepsyinmonotherapyandinpolytherapyinchildrenandadolescents |