Is there a “renal-pulmonary syndrome” in rheumatoid arthritis?
Objective: to compare the course of “rheumatoid disease” in multimorbid patients with and without interstitial lung disease (ILD).Material and methods. Two groups were formed of 1034 patients with active rheumatoid arthritis (RA) who met the 2010 ACR/EULAR criteria: one group with ILD identified by...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2024-04-01
|
| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/1561 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839574064984752128 |
|---|---|
| author | A. V. Gordeev E. A. Galushko E. V. Matyanova E. V. Pozhidaev E. G. Zotkin A. M. Lila |
| author_facet | A. V. Gordeev E. A. Galushko E. V. Matyanova E. V. Pozhidaev E. G. Zotkin A. M. Lila |
| author_sort | A. V. Gordeev |
| collection | DOAJ |
| description | Objective: to compare the course of “rheumatoid disease” in multimorbid patients with and without interstitial lung disease (ILD).Material and methods. Two groups were formed of 1034 patients with active rheumatoid arthritis (RA) who met the 2010 ACR/EULAR criteria: one group with ILD identified by high-resolution computed tomography of the lungs (n=82) and another – without ILD (n=900). In all patients, estimated glomerular filtration rate (eGFR) was determined using the Cockroft–Gault formula. The presence and stage of chronic kidney disease (CKD) was assessed depending on the eGFR level: stage I CKD was diagnosed in eGFR <89 ml/min, stage II (subclinical) – 60<eGFR <89 ml/min, stage IIIa (clinical) – 45<eGFR<59 ml/min and IIIb – 30<eGFR<45 ml/min.Results and discussion. Arterial hypertension (p=0.004), cerebrovascular disease (p=0.0001), diabetes mellitus (p=0.04), obesity, psoriasis (p=0.009) and stage II–III CKD (p=0.04) were more frequently observed in the group with ILD.Conclusion. The combination of CKD and ILD frequently found in patients with RA and the known similarity and close interrelationship of the pathogenesis of these diseases, suggest a type of “renal-pulmonary syndrome” associated with a specific variant of RA. |
| format | Article |
| id | doaj-art-d9f9065fa42f4b3a8277b09b85d4ef3d |
| institution | Matheson Library |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2024-04-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-d9f9065fa42f4b3a8277b09b85d4ef3d2025-08-04T14:00:40ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2024-04-0118210.14412/1996-7012-2024-2-51-552670Is there a “renal-pulmonary syndrome” in rheumatoid arthritis?A. V. Gordeev0E. A. Galushko1E. V. Matyanova2E. V. Pozhidaev3E. G. Zotkin4A. M. Lila5V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaObjective: to compare the course of “rheumatoid disease” in multimorbid patients with and without interstitial lung disease (ILD).Material and methods. Two groups were formed of 1034 patients with active rheumatoid arthritis (RA) who met the 2010 ACR/EULAR criteria: one group with ILD identified by high-resolution computed tomography of the lungs (n=82) and another – without ILD (n=900). In all patients, estimated glomerular filtration rate (eGFR) was determined using the Cockroft–Gault formula. The presence and stage of chronic kidney disease (CKD) was assessed depending on the eGFR level: stage I CKD was diagnosed in eGFR <89 ml/min, stage II (subclinical) – 60<eGFR <89 ml/min, stage IIIa (clinical) – 45<eGFR<59 ml/min and IIIb – 30<eGFR<45 ml/min.Results and discussion. Arterial hypertension (p=0.004), cerebrovascular disease (p=0.0001), diabetes mellitus (p=0.04), obesity, psoriasis (p=0.009) and stage II–III CKD (p=0.04) were more frequently observed in the group with ILD.Conclusion. The combination of CKD and ILD frequently found in patients with RA and the known similarity and close interrelationship of the pathogenesis of these diseases, suggest a type of “renal-pulmonary syndrome” associated with a specific variant of RA.https://mrj.ima-press.net/mrj/article/view/1561rheumatoid arthritisinterstitial lung diseasechronic kidney diseasemultimorbidityrenal-pulmonary syndrome |
| spellingShingle | A. V. Gordeev E. A. Galushko E. V. Matyanova E. V. Pozhidaev E. G. Zotkin A. M. Lila Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? Современная ревматология rheumatoid arthritis interstitial lung disease chronic kidney disease multimorbidity renal-pulmonary syndrome |
| title | Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? |
| title_full | Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? |
| title_fullStr | Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? |
| title_full_unstemmed | Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? |
| title_short | Is there a “renal-pulmonary syndrome” in rheumatoid arthritis? |
| title_sort | is there a renal pulmonary syndrome in rheumatoid arthritis |
| topic | rheumatoid arthritis interstitial lung disease chronic kidney disease multimorbidity renal-pulmonary syndrome |
| url | https://mrj.ima-press.net/mrj/article/view/1561 |
| work_keys_str_mv | AT avgordeev istherearenalpulmonarysyndromeinrheumatoidarthritis AT eagalushko istherearenalpulmonarysyndromeinrheumatoidarthritis AT evmatyanova istherearenalpulmonarysyndromeinrheumatoidarthritis AT evpozhidaev istherearenalpulmonarysyndromeinrheumatoidarthritis AT egzotkin istherearenalpulmonarysyndromeinrheumatoidarthritis AT amlila istherearenalpulmonarysyndromeinrheumatoidarthritis |