THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS

Despite progress in reducing the risk of hypertension (HT) complications, control of blood pressure (BP) levels remains inadequate. Dihydropyridine calcium channel blockers show antihypertensive effect due to significant vasoselective action with a minimal impact on a conductive system of the heart....

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Main Author: E. EL. Trisvetova
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/153
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author E. EL. Trisvetova
author_facet E. EL. Trisvetova
author_sort E. EL. Trisvetova
collection DOAJ
description Despite progress in reducing the risk of hypertension (HT) complications, control of blood pressure (BP) levels remains inadequate. Dihydropyridine calcium channel blockers show antihypertensive effect due to significant vasoselective action with a minimal impact on a conductive system of the heart. Lercanidipine is a dihydropyridine calcium channel blocker of the third generation with high lipophilicity and long-lasting action. Lercanidipine had shown both in monotherapy and in combination with ACE inhibitors or angiotensin II blockers the good antihypertensive effect with stable BP profile throughout the day, organoprotection that slowed down the progression of HT complications, metabolic neutrality and safety in mild to moderate HT.
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publisher Столичная издательская компания
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-d97c5b74416b40f18d6b71ce64d01e5d2025-07-03T07:28:22ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-0111220220810.20996/1819-6446-2015-11-2-202-208153THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONSE. EL. Trisvetova0Belarusian State Medical UniversityDespite progress in reducing the risk of hypertension (HT) complications, control of blood pressure (BP) levels remains inadequate. Dihydropyridine calcium channel blockers show antihypertensive effect due to significant vasoselective action with a minimal impact on a conductive system of the heart. Lercanidipine is a dihydropyridine calcium channel blocker of the third generation with high lipophilicity and long-lasting action. Lercanidipine had shown both in monotherapy and in combination with ACE inhibitors or angiotensin II blockers the good antihypertensive effect with stable BP profile throughout the day, organoprotection that slowed down the progression of HT complications, metabolic neutrality and safety in mild to moderate HT.https://www.rpcardio.online/jour/article/view/153arterial hypertensioncomplicationscalcium channel blockerslercanidipine
spellingShingle E. EL. Trisvetova
THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
Рациональная фармакотерапия в кардиологии
arterial hypertension
complications
calcium channel blockers
lercanidipine
title THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
title_full THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
title_fullStr THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
title_full_unstemmed THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
title_short THE EFFECTIVENESS OF LERCANIDIPINE IN REDUCING THE RISK OF ARTERIAL HYPERTENSION COMPLICATIONS
title_sort effectiveness of lercanidipine in reducing the risk of arterial hypertension complications
topic arterial hypertension
complications
calcium channel blockers
lercanidipine
url https://www.rpcardio.online/jour/article/view/153
work_keys_str_mv AT eeltrisvetova theeffectivenessoflercanidipineinreducingtheriskofarterialhypertensioncomplications
AT eeltrisvetova effectivenessoflercanidipineinreducingtheriskofarterialhypertensioncomplications