Ignatzschineria larvae Bacteremia in a Myiatic Wound Infection: A Case Report

This case report describes the fifth confirmed instance to the author's knowledge of Ignatzschineria larvae bacteremia in the United States. A 77-year-old man from western Iowa with chronic lower extremity edema and ulcers presented with acute leg pain, systemic symptoms, and maggot-infested wo...

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Bibliographic Details
Main Authors: Nicholas Mielke, FNU Monika, Stephen J. Cavalieri, Manasa Velagapudi
Format: Article
Language:English
Published: American College of Physicians 2025-07-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.1126
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Summary:This case report describes the fifth confirmed instance to the author's knowledge of Ignatzschineria larvae bacteremia in the United States. A 77-year-old man from western Iowa with chronic lower extremity edema and ulcers presented with acute leg pain, systemic symptoms, and maggot-infested wounds. Laboratory tests and imaging indicated severe infection, with blood cultures positive for gram-negative rods. Identification of I larvae was confirmed through 16S ribosomal gene sequencing. The patient received intravenous antibiotics, had below-the-knee amputation, and was discharged on a regimen of oral trimethoprim/sulfamethoxazole. This case highlights the rarity of I larvae bacteremia in nontropical regions and the need for further research.
ISSN:2767-7664