A rare HCN4 variant combined with sick sinus syndrome, left ventricular noncompaction, and complex congenital heart disease
The hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 (HCN4) gene has been reported to regulate the spontaneous depolarization of sinoatrial node cells. A novel HCN4 mutation (c.2036 G>A) may lead to sick sinus syndrome. The green fluorescent protein (GFP) and either the wil...
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Main Authors: | Fengxiao Zhang, Ning Zhao, Lin Wang, Hua Peng, Ying Jiang, Min Cheng, Feng Zhu |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
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Series: | Channels |
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Online Access: | https://www.tandfonline.com/doi/10.1080/19336950.2025.2517851 |
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