Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040
BackgroundThe present research focuses on elucidating the global burden of hypertensive heart disease (HHD) among women of childbearing age (WCBA). By utilizing all available data and adopting the methodology employed in the Global Burden of Disease (GBD) study, this study aims to comprehensively an...
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Global Women's Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fgwh.2025.1600340/full |
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| author | Zhenglong Wang Zhenglong Wang Hao Li Hao Li Hongwei Wei Baotang Liu Lei Li Zijun Li Jindong Feng Yunjie Hu Xiaobo Liu |
| author_facet | Zhenglong Wang Zhenglong Wang Hao Li Hao Li Hongwei Wei Baotang Liu Lei Li Zijun Li Jindong Feng Yunjie Hu Xiaobo Liu |
| author_sort | Zhenglong Wang |
| collection | DOAJ |
| description | BackgroundThe present research focuses on elucidating the global burden of hypertensive heart disease (HHD) among women of childbearing age (WCBA). By utilizing all available data and adopting the methodology employed in the Global Burden of Disease (GBD) study, this study aims to comprehensively analyze the epidemiological characteristics of this highly prevalent disorder.MethodsIn this research, we retrieved three key indicators—prevalence, incidence, and DALYs—related to HHD in WCBA from the GBD database for the period 1990 to 2021. Our study provides point estimates along with their corresponding 95% uncertainty intervals (UIs). The evolving trends were assessed using the EAPC and percentage change.ResultsIn 2021, the global prevalence of HHD among WCBA was 544,544 cases, resulting in 25,669 deaths. Compared to 1990, the prevalence increased by 110%, and mortality rose by 27%. From 1990 to 2021, the prevalence rate showed an upward trend (EAPC: 1.31), whereas the mortality rate exhibited a decline (EAPC: −0.51). In 2021, middle SDI regions recorded the highest prevalence rate (30.88 per 100,000), while low SDI regions had the highest mortality rate (2.44 per 100,000) and the greatest burden of DALYs (125.39 per 100,000). Among different age groups in 2021, the 45–49 age group experienced the highest number of cases (195,288) and the highest prevalence rate (82.87 per 100,000). Furthermore, HHD prevalence demonstrated a positive correlation with age.ConclusionOverall, on a global scale, the burden of HHD among WCBA has significantly increased over the past 32 years. This trend is particularly pronounced in low SDI regions and within the 45–49 age group. The findings of this study highlight the critical need for targeted interventions to address this issue. |
| format | Article |
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| institution | Matheson Library |
| issn | 2673-5059 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Global Women's Health |
| spelling | doaj-art-d904037b685e4bf49b1a8e56f57e86122025-07-11T05:24:21ZengFrontiers Media S.A.Frontiers in Global Women's Health2673-50592025-07-01610.3389/fgwh.2025.16003401600340Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040Zhenglong Wang0Zhenglong Wang1Hao Li2Hao Li3Hongwei Wei4Baotang Liu5Lei Li6Zijun Li7Jindong Feng8Yunjie Hu9Xiaobo Liu10School of Clinical Medicine, Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaSchool of Clinical Medicine, Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartment of Gynecology, Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartmentof Cardiovascular Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaBackgroundThe present research focuses on elucidating the global burden of hypertensive heart disease (HHD) among women of childbearing age (WCBA). By utilizing all available data and adopting the methodology employed in the Global Burden of Disease (GBD) study, this study aims to comprehensively analyze the epidemiological characteristics of this highly prevalent disorder.MethodsIn this research, we retrieved three key indicators—prevalence, incidence, and DALYs—related to HHD in WCBA from the GBD database for the period 1990 to 2021. Our study provides point estimates along with their corresponding 95% uncertainty intervals (UIs). The evolving trends were assessed using the EAPC and percentage change.ResultsIn 2021, the global prevalence of HHD among WCBA was 544,544 cases, resulting in 25,669 deaths. Compared to 1990, the prevalence increased by 110%, and mortality rose by 27%. From 1990 to 2021, the prevalence rate showed an upward trend (EAPC: 1.31), whereas the mortality rate exhibited a decline (EAPC: −0.51). In 2021, middle SDI regions recorded the highest prevalence rate (30.88 per 100,000), while low SDI regions had the highest mortality rate (2.44 per 100,000) and the greatest burden of DALYs (125.39 per 100,000). Among different age groups in 2021, the 45–49 age group experienced the highest number of cases (195,288) and the highest prevalence rate (82.87 per 100,000). Furthermore, HHD prevalence demonstrated a positive correlation with age.ConclusionOverall, on a global scale, the burden of HHD among WCBA has significantly increased over the past 32 years. This trend is particularly pronounced in low SDI regions and within the 45–49 age group. The findings of this study highlight the critical need for targeted interventions to address this issue.https://www.frontiersin.org/articles/10.3389/fgwh.2025.1600340/fullhypertensive heart diseaseglobal burden of diseasewomen of childbearing agecardiologypublic health |
| spellingShingle | Zhenglong Wang Zhenglong Wang Hao Li Hao Li Hongwei Wei Baotang Liu Lei Li Zijun Li Jindong Feng Yunjie Hu Xiaobo Liu Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 Frontiers in Global Women's Health hypertensive heart disease global burden of disease women of childbearing age cardiology public health |
| title | Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 |
| title_full | Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 |
| title_fullStr | Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 |
| title_full_unstemmed | Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 |
| title_short | Burden of hypertensive heart disease among women of childbearing age in global, regional, and national regions from 1990 to 2021 and projection until 2040 |
| title_sort | burden of hypertensive heart disease among women of childbearing age in global regional and national regions from 1990 to 2021 and projection until 2040 |
| topic | hypertensive heart disease global burden of disease women of childbearing age cardiology public health |
| url | https://www.frontiersin.org/articles/10.3389/fgwh.2025.1600340/full |
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