Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment

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Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment

IntroductionOvarian cancer is the most lethal gynecological malignancy. Deepening our knowledge of the interactions within the tumor microenvironment (TME) is important for discovering new targeted treatment strategies. Transglutaminase 2 (TG2) is a protein implicated in many biological and pathophy...

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Main Authors:	Dalia Ibrahim, Melanie Grondin, Kristianne Galpin, Sara Asif, Emily Thompson, Sarah Nersesian, John Abou-Hamad, Maryam Echaibi, Galaxia M. Rodriguez, Pauline Navals, Elizabeth Macdonald, Brianna Ryan, David P. Cook, Jeffrey W. Keillor, Barbara C. Vanderhyden
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	ovarian cancer transglutaminase 2 immune modulation targeted therapy metastasis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1639853/full
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