Mediator complex: update of key insights into transcriptional regulation of ancestral framework and its role in cardiovascular diseases

Abstract Transcriptional regulation plays a pivotal role in coordinating the complex morphogenetic and molecular events involved in heart development and function. In the early stages of cardiovascular diseases (CVDs), the Mediator complex (MED) performs a variety of essential functions. While initi...

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Bibliographic Details
Main Authors: Concetta Schiano, Claudio Napoli
Format: Article
Language:English
Published: BMC 2025-06-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02720-2
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