THE ROLE OF CD200/CD200R INTERACTIONS IN THE FORMATION OF IMMUNOLOGICAL TOLERANCE IN TRANSPLANTATION AND PREGNANCY

THE ROLE OF CD200/CD200R INTERACTIONS IN THE FORMATION OF IMMUNOLOGICAL TOLERANCE IN TRANSPLANTATION AND PREGNANCY

The transmembrane CD200 glycoprotein belongs to the immunoglobulin family and it is widely represented on a variety of cell types, while its structurally similar CD200R receptor is expressed, mainly, on myeloid and lymphoid cells. An immunomodulatory role of CD200 and CD200R interaction is to activa...

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Bibliographic Details
Main Authors: A. S. Arefieva, A. A. Babayan, E. O. Stepanova, T. V. Dontsova, S. V. Pavlovich, L. V. Krechetova, M. A. Nikolaeva
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2018-12-01
Series:Медицинская иммунология
Subjects:
cd200
allograft
pregnancy
immune tolerance
inhibitory receptor
recurrent abortion
Online Access:https://www.mimmun.ru/mimmun/article/view/1665
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