Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking approaches

Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking approaches

Scrophulariae Radix is a traditional Chinese medicine used to treat neoplasms in previous publications. Nevertheless, how the Scrophulariae Radix chemical constituents treat neoplasm still needs to be clarified. Herein, we combined the response surface method, UPLC-ESI-MS/MS, network pharmacology, m...

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Bibliographic Details
Main Authors: Shu-jie Yu, Xiao-bin Kong, Xin Jin, Meng-yi Shan, Gang Cheng, Pei-lu Wang, Wen-long Li, Pei-yuan Zhao, Yun-jie Sheng, Bing-qian He, Qi Shi, Hua-qiang Li, Qi-ming Zhao, Lu-ping Qin, Xiong-yu Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Plant Science
Subjects:
Scrophulariae Radix
neoplasm
response surface analysis method
UPLC-ESI-MS/MS
network pharmacology
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1615076/full
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