Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema

Facklamia is an emerging pathogen in human beings and only a few clinical cases were reported in the literature. We detected the presence of this unusual microbe among the skin flora of three patients with filarial lymphedema in a 16S rRNA-based metagenomic study on the skin microbiome. To our knowl...

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Main Authors: Danapriyaa Dharmalingam, Janani Semalaiyappan, Sankari Thirumal, Vijesh Sreedhar Kuttiatt
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1624288/full
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author Danapriyaa Dharmalingam
Janani Semalaiyappan
Sankari Thirumal
Vijesh Sreedhar Kuttiatt
author_facet Danapriyaa Dharmalingam
Janani Semalaiyappan
Sankari Thirumal
Vijesh Sreedhar Kuttiatt
author_sort Danapriyaa Dharmalingam
collection DOAJ
description Facklamia is an emerging pathogen in human beings and only a few clinical cases were reported in the literature. We detected the presence of this unusual microbe among the skin flora of three patients with filarial lymphedema in a 16S rRNA-based metagenomic study on the skin microbiome. To our knowledge, this is the first report of detection of this microbe in patients affected with filarial lymphedema. Further investigations are required to elucidate the role of Facklamia in secondary skin and soft tissue infection of filarial lymphedema patients.
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publishDate 2025-07-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Cellular and Infection Microbiology
spelling doaj-art-d7c83c90a3c84e28b62d9cf090d1f4a62025-07-31T05:37:22ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882025-07-011510.3389/fcimb.2025.16242881624288Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedemaDanapriyaa DharmalingamJanani SemalaiyappanSankari ThirumalVijesh Sreedhar KuttiattFacklamia is an emerging pathogen in human beings and only a few clinical cases were reported in the literature. We detected the presence of this unusual microbe among the skin flora of three patients with filarial lymphedema in a 16S rRNA-based metagenomic study on the skin microbiome. To our knowledge, this is the first report of detection of this microbe in patients affected with filarial lymphedema. Further investigations are required to elucidate the role of Facklamia in secondary skin and soft tissue infection of filarial lymphedema patients.https://www.frontiersin.org/articles/10.3389/fcimb.2025.1624288/fullFacklamiafilarial lymphedemaskin microbiomeopportunistic pathogen16S rRNA-based metagenomics
spellingShingle Danapriyaa Dharmalingam
Janani Semalaiyappan
Sankari Thirumal
Vijesh Sreedhar Kuttiatt
Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
Frontiers in Cellular and Infection Microbiology
Facklamia
filarial lymphedema
skin microbiome
opportunistic pathogen
16S rRNA-based metagenomics
title Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
title_full Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
title_fullStr Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
title_full_unstemmed Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
title_short Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
title_sort unveiling facklamia detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema
topic Facklamia
filarial lymphedema
skin microbiome
opportunistic pathogen
16S rRNA-based metagenomics
url https://www.frontiersin.org/articles/10.3389/fcimb.2025.1624288/full
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