Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty
The objective was to compare the efficacy and safety of morphine in neuraxial blocks during knee arthroplasty.Materials and methods. A retrospective analysis of 60 medical histories of patients who underwent total knee arthroplasty for the period from 2017 to 2019 was performed. All patients were op...
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| Language: | Russian |
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New Terra Publishing House
2023-02-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/763 |
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| author | S. V. Sokolov V. A. Glushchenko A. E. Mikhnin |
| author_facet | S. V. Sokolov V. A. Glushchenko A. E. Mikhnin |
| author_sort | S. V. Sokolov |
| collection | DOAJ |
| description | The objective was to compare the efficacy and safety of morphine in neuraxial blocks during knee arthroplasty.Materials and methods. A retrospective analysis of 60 medical histories of patients who underwent total knee arthroplasty for the period from 2017 to 2019 was performed. All patients were operated under general anesthesia with mechanical ventilation in combination with epidural or spinal analgesia with opiates. Patients of the 1st group (n=20) after catheterization of the epidural space at the level of L1–2 were injected with a morphine solution 1% – 0.3 ml epidurally. Patients of the 2nd group (n=20) were injected with a morphine solution 1% – 0.01 ml intrathecally at the level of L3–4. Patients of the 3rd group (n=20) underwent standard combined anesthesia: general anesthesia with mechanical ventilation and epidural analgesia at the level of L1–2 with a solution of 0.2% ropivacaine in the form of an infusion of 6 ml/hour. All patients received infusion of 0.2% solution of ropivacaine epidurally 6 ml/hour at the level of L1–2 in the postoperative period.The incidence of nausea, vomiting, pruritus, headache and the level of postoperative pain syndrome were assessed on a numerical rating scale 6 hours after the end of the surgery.Results. The level of pain syndrome in patients who received intrathecal and epidural analgesia with morphine was equally low, while in patients who received epidural analgesia with ropivacaine, the level of pain syndrome was statistically significantly higher, which required the additional prescription of non-steroidal anti-inflammatory drugs and/or narcotic analgesics parenterally. The frequency of nausea, vomiting, pruritus and headaches was maximum in the 2nd group, significantly lower in the 1st, while in the 3rd, pruritus did not occur.Conclusion. The use of morphine in neuraxial block in knee arthroplasty has a positive effect on the quality of anesthesia and postoperative pain relief. |
| format | Article |
| id | doaj-art-d7191f57c2cf4e46945d1a0e7ea6c4b7 |
| institution | Matheson Library |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2023-02-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-d7191f57c2cf4e46945d1a0e7ea6c4b72025-08-04T10:20:48ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532023-02-01201364010.24884/2078-5658-2023-20-1-36-40578Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplastyS. V. Sokolov0V. A. Glushchenko1A. E. Mikhnin2Hospital for War VeteransNMRC of Oncology named after N.N. Petrov; Pavlov UniversityNMRC of Oncology named after N.N. Petrov; North-Western State Medical University named after I.I. MechnikovThe objective was to compare the efficacy and safety of morphine in neuraxial blocks during knee arthroplasty.Materials and methods. A retrospective analysis of 60 medical histories of patients who underwent total knee arthroplasty for the period from 2017 to 2019 was performed. All patients were operated under general anesthesia with mechanical ventilation in combination with epidural or spinal analgesia with opiates. Patients of the 1st group (n=20) after catheterization of the epidural space at the level of L1–2 were injected with a morphine solution 1% – 0.3 ml epidurally. Patients of the 2nd group (n=20) were injected with a morphine solution 1% – 0.01 ml intrathecally at the level of L3–4. Patients of the 3rd group (n=20) underwent standard combined anesthesia: general anesthesia with mechanical ventilation and epidural analgesia at the level of L1–2 with a solution of 0.2% ropivacaine in the form of an infusion of 6 ml/hour. All patients received infusion of 0.2% solution of ropivacaine epidurally 6 ml/hour at the level of L1–2 in the postoperative period.The incidence of nausea, vomiting, pruritus, headache and the level of postoperative pain syndrome were assessed on a numerical rating scale 6 hours after the end of the surgery.Results. The level of pain syndrome in patients who received intrathecal and epidural analgesia with morphine was equally low, while in patients who received epidural analgesia with ropivacaine, the level of pain syndrome was statistically significantly higher, which required the additional prescription of non-steroidal anti-inflammatory drugs and/or narcotic analgesics parenterally. The frequency of nausea, vomiting, pruritus and headaches was maximum in the 2nd group, significantly lower in the 1st, while in the 3rd, pruritus did not occur.Conclusion. The use of morphine in neuraxial block in knee arthroplasty has a positive effect on the quality of anesthesia and postoperative pain relief.https://www.vair-journal.com/jour/article/view/763spinal anesthesiaepidural analgesiamorphinenauseavomitingprurituspain syndromearthroplastyknee joint |
| spellingShingle | S. V. Sokolov V. A. Glushchenko A. E. Mikhnin Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty Вестник анестезиологии и реаниматологии spinal anesthesia epidural analgesia morphine nausea vomiting pruritus pain syndrome arthroplasty knee joint |
| title | Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| title_full | Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| title_fullStr | Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| title_full_unstemmed | Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| title_short | Frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| title_sort | frequency of typical complications of morphine during its intrathecal and epidural introduction in knee arthroplasty |
| topic | spinal anesthesia epidural analgesia morphine nausea vomiting pruritus pain syndrome arthroplasty knee joint |
| url | https://www.vair-journal.com/jour/article/view/763 |
| work_keys_str_mv | AT svsokolov frequencyoftypicalcomplicationsofmorphineduringitsintrathecalandepiduralintroductioninkneearthroplasty AT vaglushchenko frequencyoftypicalcomplicationsofmorphineduringitsintrathecalandepiduralintroductioninkneearthroplasty AT aemikhnin frequencyoftypicalcomplicationsofmorphineduringitsintrathecalandepiduralintroductioninkneearthroplasty |