Epothilone B from Aspergillus fumigatus with a strong antiproliferative and anti-tubulin polymerizing activities; apoptosis, and cell cycle analyses
Abstract Epothilones were designated as one of the most recognized chemotherapeutic agents towards the drug-resistant tumors, for their higher potency to bind and stabilize the β-tubulin arrays, stopping the cell cycle. Epothilones were chemically resolved from Aspergillus fumigatus # MN744705.1, th...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | BMC Microbiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12866-025-04086-1 |
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