Emerging mechanisms and implications of m6A in CVDs: potential applications of natural products

QR Code

Emerging mechanisms and implications of m6A in CVDs: potential applications of natural products

N6-methyladenosine (m6A) RNA methylation is the most common, abundant, and reversible epigenetic modification of RNAs, and it directs many essential processes in RNAs post-transcriptionally. It has been shown that m6A modification affects cardiovascular diseases (CVDs) by regulating RNA splicing, lo...

Full description

Saved in:

Bibliographic Details
Main Authors:	Hui Wang, Yun Zhang, Xiao Jiang, Guichun Liu, Shujian Xu, Jinbiao He, Xudong He, Ting Xiao, Lijuan Wang, LiJing Xiao, Xinhui Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	m6A methylation cardiovascular diseases natural products biological processes epigenetic modification
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1559064/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Dynamic Rendition of Adipose Genes Under Epigenetic Regulation: Revealing New Mechanisms of Obesity Occurrence
by: Weijing Wen, et al.
Published: (2025-07-01)

Effects of RNA m6A on the formation of multi-petalization in Magnolia wufengensis: Mechanistic insights and gene expression analysis
by: Cunjie Li, et al.
Published: (2025-07-01)

Epigenetic mechanisms linking pregnancy complications to cardiovascular disease in offspring
by: Kazim Raza Talpur, et al.
Published: (2024-11-01)

The role of epigenetics in pulmonary fibrosis: recent advances in mechanistic insights and therapeutic implications
by: Jingru Huang, et al.
Published: (2025-07-01)

DNA Methylation: A Key Regulator in Male and Female Reproductive Outcomes
by: Adedeji O. Adetunji, et al.
Published: (2025-07-01)

The Roles of Epigenetics in the Interplay Between Beneficial Rhizobacteria and Plants
by: Rui Zou, et al.
Published: (2025-06-01)

Epigenetic Mechanisms in <i>Apis melifera</i>: From Development to Environmental Adaptation
by: Xiexin Hu, et al.
Published: (2025-07-01)

Epigenetics in Plant Response to Climate Change
by: Wei Zhou, et al.
Published: (2025-05-01)

Advances in the Epigenetic Mechanisms of Diabetic Nephropathy Pathogenesis
by: Zhang C, et al.
Published: (2025-07-01)

Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs
by: Hajar Erraji, et al.
Published: (2025-07-01)

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis
by: Shuang Guo, et al.
Published: (2025-07-01)

Advances in research on RNA methylation and cancer radiotherapy resistance
by: Hui Liu, et al.
Published: (2025-07-01)

Novel Insights into the Regulatory Role of N6-Methyladenosine in the Pathogenesis and Clinical Treatment of Osteoarthritis: Research Status and Prospect
by: He M, et al.
Published: (2025-05-01)

The Dynamic Interactions of m6A Modification and R-Loops: Implications for Genome Stability
by: Nicholas Kim, et al.
Published: (2025-06-01)

Effect of m<sup>6</sup>A Recognition Protein YTHDC1 on Skeletal Muscle Growth
by: Huijun Huang, et al.
Published: (2025-07-01)

Commentary on “Ferroptosis, M6A and immune checkpoint-related gene expression in the middle temporal gyrus of the Alzheimer's disease brain”
by: Ziyu Liu, et al.
Published: (2025-06-01)

Regulation of the Immune System in Aging: Focus on Epigenetic Mechanisms
by: K. A. Aitbaev, et al.
Published: (2022-02-01)

Epigenetic modulation in medicine: Regulation of gene expression in the context of pathogenesis and therapy
by: M. A. Omarov, et al.
Published: (2024-12-01)

The Good, the Bad, and the Epigenetic: Stress-Induced Metabolite Regulation and Transgenerational Effects
by: Saida Ibragić, et al.
Published: (2025-03-01)

Epigenetic Alterations in Cancer: The Therapeutic Potential of Epigenetic Drugs in Cancer Therapy
by: Preeti Gupta
Published: (2025-04-01)

INFLUENCE OF SMOKING ON THE METHYLIZING STATUS OF DESOXYRIBONUCLEIC ACID
by: A. V. Kiseleva, et al.
Published: (2015-12-01)

Analysis of cytosine methylation in early generations of resynthesized Brassica napus
by: Li-ping RAN, et al.
Published: (2016-06-01)

The epigenetic regulatory network of long noncoding RNAs in hepatocellular carcinoma
by: Zhaoqi Shi, et al.
Published: (2025-09-01)

Epigenetic Rewiring of Protein Kinase Signalling in T-Cell Acute Lymphoblastic Leukaemia
by: Claudina A. Pérez-Novo, et al.
Published: (2025-04-01)

Role of epigenetics and the high-throughput sensing techniques to detect stress adaptation mechanisms in crop plants: A mini review
by: Dipan Adhikari, et al.
Published: (2023-10-01)

Epigenetic DNA Methylation Under the Influence of Low-Dose Ionizing Radiation, and Supplementation with Vitamin B12 and Folic Acid: Harmful or Beneficial for Professionals?
by: Borivoje Savic, et al.
Published: (2025-05-01)

A Cost-Effective Saliva-Based Human Epigenetic Clock Using 10 CpG Sites Identified with the Illumina EPIC 850k Array
by: Christopher Collins, et al.
Published: (2025-06-01)

METTL14 and FTO mediated m6A modification regulate PCV2 replication by affecting miR-30a-5p maturity
by: Chen Li, et al.
Published: (2023-12-01)

Methylation profile of individuals with sickle cell trait
by: Ana Gabriela Vasconcelos, et al.
Published: (2025-12-01)

The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer
by: Li Qiu, et al.
Published: (2025-09-01)

EPIGENETIC EFFECTS OF ENZASTAURIN – A NEW ASPECT IN THE MECHANISM OF ACTION OF AN ANTICANCER DRUG FROM PROTEIN KINASE INHIBITORS
by: V. P. Maksimova, et al.
Published: (2020-09-01)

The Role of Epigenetics in Cardiovascular Disease: Providing Insights into Disease Mechanisms and Evaluating Therapeutic Potential for Future Treatment Strategies
by: Omar Elsaka
Published: (2025-07-01)

RNA Binding Motif Protein 15 (RBM15): Structure, Function and Its Research Progress in Tumors
by: Long X, et al.
Published: (2025-07-01)

M6A RNA modification: focusing on non-small cell lung cancer progression, therapeutic strategies and challenges
by: Yuyang Yan, et al.
Published: (2025-07-01)

Epigenetic Biomarkers of Cardiovascular Risk in Frail Patients—A Scope Review
by: Stanisław Wawrzyniak, et al.
Published: (2025-06-01)

Epigenetics of obesity
by: O. M. Drapkina, et al.
Published: (2020-12-01)

Search for differentially methylated regions in ancient and modern genomes
by: D. D. Borodko, et al.
Published: (2023-12-01)

The specifics of CpG islets methylation of some genes of peripheral blood T-lymphocytes in breast cancer patients before and after treatment
by: T. G. Goncharova, et al.
Published: (2023-07-01)

Ketone body, as an emerging modulator of metabolic reprogramming and epigenetics in breast cancer
by: Fatemeh Mehdikhani, et al.
Published: (2025-09-01)

Research advance of N <sup>6</sup>-methyladenosine (m<sup>6</sup>A) in insect
by: ZHAO Shudi, et al.
Published: (2021-06-01)