PECULIARITIES OF LABORATORY DIAGNOSTICS OF EXPERIMENTAL BRUCELLOSIS CAUSED BY SAND L-FORMS OF CAUSATIVE AGENT
Comparative evaluation, of bacteriological, serological and PCR diagnostic methods was resulted, at experimental brucellosis in guinea pigs infected, with. S- and. L-forms of the causative agent in different periods of the infection. It was shown that Brucella S-forms were isolated, during six month...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2012-04-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/799 |
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| Summary: | Comparative evaluation, of bacteriological, serological and PCR diagnostic methods was resulted, at experimental brucellosis in guinea pigs infected, with. S- and. L-forms of the causative agent in different periods of the infection. It was shown that Brucella S-forms were isolated, during six months, L-forms - about one month, by a bacteriological method. Positive PCR results were observed about six months after S- and. L-form infection in animals. Positive slide agglutination, of guinea pig blood sera was revealed, till 12 months by a corpuscular diagnosticum with. S- and. L-forms of Brucella. Complex use of bacteriological, PCR and. serological methods for laboratory diagnostics of atypical brucellosis caused, by Brucella L-form allows to obtain more reliable information, about epizootological-epidemiological situation in non-manifested (non-clinical) infection foci. |
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| ISSN: | 2541-9420 2587-9596 |