Inflammatory linear verrucous epidermal nevus (ILVEN): a clinical case and review of the literature
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disorder characterized by verrucose, linearly arranged growths on the skin on one side of the body and extremities. The etiopathogenesis of the disease remains not fully understood. To date, the main cause of the development of thi...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Open Systems Publication
2022-11-01
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| Series: | Лечащий Врач |
| Subjects: | |
| Online Access: | https://journal.lvrach.ru/jour/article/view/980 |
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| Summary: | Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disorder characterized by verrucose, linearly arranged growths on the skin on one side of the body and extremities. The etiopathogenesis of the disease remains not fully understood. To date, the main cause of the development of this pathology is considered to be somatic mutations leading to the appearance of genetic mosaicism. The clinical picture of the disease is quite typical and consists of verrucous, linearly located, unilateral growths localized both on the trunk and on the extremities. Despite the typical clinical picture, practitioners may experience difficulties in making a diagnosis during routine appointments due to the low incidence of this pathology. Also, diagnostic difficulties are due to the fact that some chronic dermatoses (some forms of lichen planus and psoriasis, other types of congenital epidermal nevi, Darier's disease, linear porokeratosis) have similar clinical manifestations to ILVEN. In addition to the similarity of clinical manifestations, there is also a commonality of the clinical picture in histopathological examination (for example, ILVEN and psoriasis), which also complicates the process of differential diagnosis and diagnosis. A correctly established diagnosis of inflammatory linear verrucous epidermal nevus can play a decisive role in saving the patient's life, because. Often, the presence of ILVEN in a patient is a marker of other severe comorbid disorders, including the pathology of various organs and systems and the presence of neoplasia. Identification and control of comorbid disorders in this case plays a decisive role in saving the life and health of the patient. ILVEN therapy includes both conservative and surgical methods. The choice of treatment method largely depends on the clinical picture of the disease. This article presents a clinical case of congenital linear verrucous epidermal nevus, as well as a review of the literature covering the known aspects of etiopathogenesis, clinical presentation, diagnosis and treatment of the disease. |
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| ISSN: | 1560-5175 2687-1181 |