Investigation of catalytic oxidation of 4-nitroethylbenzene by ozone to 4-nitroacetophenone – an intermediate in the synthesis of antibiotics
4-Nitroacetophenone is an important intermediate for the manufacture of broad-spectrum antibiotics, in particular chloramphenicol. Existing methods of ketone synthesis are imperfect. The disadvantage of the simplest of them (the oxidation of 4-nitroethylbenzene by oxygen at atmospheric pressure and...
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Main Authors: | A. H. Halstyan, A. S. Bushuiev |
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Format: | Article |
Language: | English |
Published: |
Zaporizhzhia State Medical and Pharmaceutical University
2021-07-01
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Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
Subjects: | |
Online Access: | http://pharmed.zsmu.edu.ua/article/view/230051/235015 |
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