Wnt-dependent mechanism of the apical constriction of roof plate cells in developing mouse spinal cord
Apical constriction of epithelial cells usually occurs in a local portion of epithelial sheet, which results in bending of epithelial tissues. However, it is uncertain whether diffusible signal molecules, like Wnt, regulate such locally restricted events. Here, we show that Wnt ligands are required...
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Main Authors: | Takuma Shinozuka, Tadashi Okubo, Noriaki Sasai, Shinji Takada |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1571770/full |
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