Clinical and Electrical Evolution of “Pseudo” Spike–Wave Activation in Sleep EEG Patterns in Self-Limited Childhood Epilepsies
The purpose of this study was to identify the pseudo spike–wave activation in sleep (SWAS) patterns in the electroencephalogram (EEG) of self-limited focal epilepsies of childhood (SeLFE) and study their clinical and electrical evolution. Sleep EEG and clinical data of children aged 2–12 years with...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-05-01
|
| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/aian.aian_899_24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The purpose of this study was to identify the pseudo spike–wave activation in sleep (SWAS) patterns in the electroencephalogram (EEG) of self-limited focal epilepsies of childhood (SeLFE) and study their clinical and electrical evolution. Sleep EEG and clinical data of children aged 2–12 years with SeLFE and pseudo-SWAS were collected retrospectively from our EEG database and were followed periodically every 6 months with clinical, EEG, and neurocognitive assessments. Nine children were identified and were grouped as follows: (a) pseudo-SWAS pattern caused by type 1 occipitofrontal spikes in five children, who had no clinical worsening on follow-up, and this pattern resolved within 3 years; (b) pseudo-SWAS pattern without occipitofrontal spikes in three children that was caused by diffusion of pre-existing focal spikes; and (c) pseudo-SWAS pattern induced by antiseizure medication in one child, which completely resolved on withdrawing the medication. Electro-clinical dissociation occurred in pseudo-SWAS, and none of them evolved to developmental and/or epileptic encephalopathy with SWAS. Identification of these patterns helps to avoid inadvertent use of antiseizure medications and immunomodulators. |
|---|---|
| ISSN: | 0972-2327 1998-3549 |