IL-17 in Protective Immunity to Vaginal Candidiasis
Vulvovaginal candidiasis (VVC) is caused by Candida albicans affects a significant number of women during their reproductive ages. Th17 cells play a major role in coordinating the host defense in oropharyngeal candidiasis. In this study we investigated the involvement of the Th17 response in an anim...
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| Language: | English |
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University of Baghdad, College of Science for Women
2016-03-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2139 |
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| author | Baghdad Science Journal |
| author_facet | Baghdad Science Journal |
| author_sort | Baghdad Science Journal |
| collection | DOAJ |
| description | Vulvovaginal candidiasis (VVC) is caused by Candida albicans affects a significant number of women during their reproductive ages. Th17 cells play a major role in coordinating the host defense in oropharyngeal candidiasis. In this study we investigated the involvement of the Th17 response in an animal model of vulvovaginal candidiasis (VVC). The present study aimed to shed light on detect concentration of the IL-17 of infected animal and control . A direct Enzyme Linked Immunosorbent Assay (ELISA) was used to quantify IL-17 concentrations in 30 infected animal with VVC and 10 control group. Rats were intravaginally inoculated with C.albicans, and vaginal lavage fluids, serum were evaluated for proinflammatory cytokine IL-17 The data suggest that IL-17, produced by vaginal cells, particularly CD4 T cells, detected in the vaginal wash and serum during the infection, reaching a maximum 14 days after the challenge. |
| format | Article |
| id | doaj-art-d36e7e9a9a9d4a71a4f60589d7b7e47d |
| institution | Matheson Library |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2016-03-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-d36e7e9a9a9d4a71a4f60589d7b7e47d2025-08-02T20:14:55ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862016-03-0113110.21123/bsj.13.1.31-35IL-17 in Protective Immunity to Vaginal CandidiasisBaghdad Science JournalVulvovaginal candidiasis (VVC) is caused by Candida albicans affects a significant number of women during their reproductive ages. Th17 cells play a major role in coordinating the host defense in oropharyngeal candidiasis. In this study we investigated the involvement of the Th17 response in an animal model of vulvovaginal candidiasis (VVC). The present study aimed to shed light on detect concentration of the IL-17 of infected animal and control . A direct Enzyme Linked Immunosorbent Assay (ELISA) was used to quantify IL-17 concentrations in 30 infected animal with VVC and 10 control group. Rats were intravaginally inoculated with C.albicans, and vaginal lavage fluids, serum were evaluated for proinflammatory cytokine IL-17 The data suggest that IL-17, produced by vaginal cells, particularly CD4 T cells, detected in the vaginal wash and serum during the infection, reaching a maximum 14 days after the challenge.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2139"IL-17, ELISA, Vaginal Candidiasis" |
| spellingShingle | Baghdad Science Journal IL-17 in Protective Immunity to Vaginal Candidiasis مجلة بغداد للعلوم "IL-17, ELISA, Vaginal Candidiasis" |
| title | IL-17 in Protective Immunity to Vaginal Candidiasis |
| title_full | IL-17 in Protective Immunity to Vaginal Candidiasis |
| title_fullStr | IL-17 in Protective Immunity to Vaginal Candidiasis |
| title_full_unstemmed | IL-17 in Protective Immunity to Vaginal Candidiasis |
| title_short | IL-17 in Protective Immunity to Vaginal Candidiasis |
| title_sort | il 17 in protective immunity to vaginal candidiasis |
| topic | "IL-17, ELISA, Vaginal Candidiasis" |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2139 |
| work_keys_str_mv | AT baghdadsciencejournal il17inprotectiveimmunitytovaginalcandidiasis |