REPARATION SYSTEM GENES: POPULATION DIFFERENCES IN HEREDITARY OVARIAN AND BREAST CANCER DETERMINED BY NEXT-GENERATION SEQUENCING

REPARATION SYSTEM GENES: POPULATION DIFFERENCES IN HEREDITARY OVARIAN AND BREAST CANCER DETERMINED BY NEXT-GENERATION SEQUENCING

Introduction. Development of hereditary ovarian cancer (OC) and breast cancer (BC) is caused by genetic abnormalities in the DNA reparation system consisting of more than 100 genes. However, currently in the majority of medical centers in Russia, diagnosis of hereditary OC and BC consists of determi...

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Bibliographic Details
Main Authors: O. I. Brovkina, M. G. Gordiev, R. F. Enikeev, M. O. Druzhkov, L. Kh. Shigapova, E. I. Shagimardanova, O. А. Gusev, V. V. Kosiy, D. S. Khodyrev, A. G. Kedrova, R. Sh. Khasanov, A. G. Nikitin
Format: Article
Language:Russian
Published: ABV-press 2017-06-01
Series:Опухоли женской репродуктивной системы
Subjects:
hereditary breast cancer
hereditary ovarian cancer
mutation
brca1/brca2 genes
genes of dna reparation system
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/544
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