Protective effect of hydroxytyrosol against hyperglycemia-induced phosphatidylserine exposure in human erythrocytes: focus on dysregulation of calcium homeostasis and redox balance

Protective effect of hydroxytyrosol against hyperglycemia-induced phosphatidylserine exposure in human erythrocytes: focus on dysregulation of calcium homeostasis and redox balance

Diabetes is a widespread chronic disease that poses serious health concerns due to its numerous associated complications, including an increased risk of cardiovascular diseases. Under conditions of prolonged hyperglycemia, erythrocytes (RBC) undergo the breakdown of the natural phospholipid asymmetr...

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Bibliographic Details
Main Authors: Rosaria Notariale, Claudia Moriello, Nicola Alessio, Vitale Del Vecchio, Luigi Mele, Pasquale Perrone, Caterina Manna
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
Subjects:
Calcium
Hydroxytyrosol
Hyperglycemia- phosphatidylserine- red blood cells
Redox balance
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002964
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