Glycosylation of canine tetherin is essential for its antiviral activity against H3N2 canine influenza virus

Glycosylation of canine tetherin is essential for its antiviral activity against H3N2 canine influenza virus

Tetherin is an interferon-induced-expressing transmembrane protein that utilizes a unique topology to restrict the release of enveloped viruses from the surface of the cell membrane. N-linked glycosylation plays an important role in protein post-translational modifications. To investigate the role o...

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Bibliographic Details
Main Authors: Liang Xu, Yuwen Hou, Shizhe Liu, Yixin Dai, Jiajun Ou, Shaotang Ye, Zhen Wang, Gang Lu, Shoujun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Veterinary Science
Subjects:
tetherin
N-linked glycosylation
mutation
canine influenza virus (CIV)
antiviral activity
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1641963/full
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