IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE

We reviewed the results of investigation which enrolled 69 patients with locally advanced breast cancer. Patients were divided into two groups. Conventional preoperative multi-agent chemotherapy with Cyclophosphamide, Metotrexate and 5-FU (CMF scheme) was car- ried out to patients of the first group...

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Main Author: L. T. Alimkhodzhayeva
Format: Article
Language:Russian
Published: ABV-press 2014-09-01
Series:Опухоли женской репродуктивной системы
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/348
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author L. T. Alimkhodzhayeva
author_facet L. T. Alimkhodzhayeva
author_sort L. T. Alimkhodzhayeva
collection DOAJ
description We reviewed the results of investigation which enrolled 69 patients with locally advanced breast cancer. Patients were divided into two groups. Conventional preoperative multi-agent chemotherapy with Cyclophosphamide, Metotrexate and 5-FU (CMF scheme) was car- ried out to patients of the first group, whereas AC scheme (Doxorubicin and Cyclophosphan) was implemented in the second group. To all participators chemotherapy was given during hyperglycemic state with serum glucose concentration of 14—15 mmol/l. The main purpose of the study is to evaluate the appropriateness of therapy according to the intensity of medical pathomorphosis and level of immunologic defense.
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institution Matheson Library
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publishDate 2014-09-01
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series Опухоли женской репродуктивной системы
spelling doaj-art-d17a61cb0aa54ca098f187ed1d348e962025-08-04T14:33:39ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-09-0102353710.17650/1994-4098-2008-0-2-35-37364IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATEL. T. Alimkhodzhayeva0Cancer Research Center of Public Health Ministry of Republic Uzbekistan, TashkentWe reviewed the results of investigation which enrolled 69 patients with locally advanced breast cancer. Patients were divided into two groups. Conventional preoperative multi-agent chemotherapy with Cyclophosphamide, Metotrexate and 5-FU (CMF scheme) was car- ried out to patients of the first group, whereas AC scheme (Doxorubicin and Cyclophosphan) was implemented in the second group. To all participators chemotherapy was given during hyperglycemic state with serum glucose concentration of 14—15 mmol/l. The main purpose of the study is to evaluate the appropriateness of therapy according to the intensity of medical pathomorphosis and level of immunologic defense.https://ojrs.abvpress.ru/ojrs/article/view/348
spellingShingle L. T. Alimkhodzhayeva
IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
Опухоли женской репродуктивной системы
title IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
title_full IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
title_fullStr IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
title_full_unstemmed IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
title_short IMMUNOMORPHOLOGIC CHANGES IN TUMOR TISSUE OF PATIENTS WITH BREAST CANCER INDUCED BY NEOADJUVANT CHEMOTHERAPY CARRIED OUT IN ARTIFICIALLY HYPERGLYCEMIC STATE
title_sort immunomorphologic changes in tumor tissue of patients with breast cancer induced by neoadjuvant chemotherapy carried out in artificially hyperglycemic state
url https://ojrs.abvpress.ru/ojrs/article/view/348
work_keys_str_mv AT ltalimkhodzhayeva immunomorphologicchangesintumortissueofpatientswithbreastcancerinducedbyneoadjuvantchemotherapycarriedoutinartificiallyhyperglycemicstate