Pharmacokinetic properties of the preparations of protein origin

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Pharmacokinetic properties of the preparations of protein origin

Biological preparations differ substantially from low molecular weight chemicals in molecular weight, multidimensional structure of an active substance, presence of post-translational modifications, composition of impurities and excipients, drug manufacturing process, etc. These specific features of...

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Bibliographic Details
Main Authors:	A. A. Soldatov, Zh. I. Avdeeva, N. A. Alpatova, N. V. Medunitsyn, S. L. Lysikova, V. A. Merkulov
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	pharmacokinetics absorption bioavailability distribution metabolism biological preparation monoclonal antibodies фармакокинетика всасывание биодоступность распределение метаболизм биологические препараты моноклональные антитела
Online Access:	https://www.biopreparations.ru/jour/article/view/11
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