The use of corticosteroids in the treatment of ulcerative colitis: A brief overview
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by the relapsing inflammation of the colonic mucosa. Corticosteroids have long been a cornerstone in the management of moderate to severe UC, particularly during acute flares. This review aims to provide a focused overview...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Serbian |
| Published: |
Pharmaceutical Association of Serbia, Belgrade, Serbia
2025-01-01
|
| Series: | Arhiv za farmaciju |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2025/0004-19632503167R.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by the relapsing inflammation of the colonic mucosa. Corticosteroids have long been a cornerstone in the management of moderate to severe UC, particularly during acute flares. This review aims to provide a focused overview of the rationale behind corticosteroid use, including their mechanisms of action, clinical efficacy, and challenges in everyday practice such as steroid dependency, adverse effects, and inappropriate long-term use. Despite their effectiveness in inducing remission, corticosteroids are not suitable for maintenance therapy and should be used judiciously in combination with other treatments. Current best-practice recommendations emphasize minimizing steroid exposure and encouraging the use of steroid-sparing agents. Close monitoring by specialists remains essential for optimizing outcomes and ensuring patient safety. |
|---|---|
| ISSN: | 0004-1963 2217-8767 |