THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES
The symptoms similar to those detected in rheumatic diseases in patients infected with human immunodeficiency virus (HIV) are due to various pathogenetic mechanisms (immune cell imbalance, antibody production, etc.). The occurrence of rheumatic symptoms and syndromes in HIV infection can lead to dia...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2018-09-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2601 |
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| author | E. Yu. Ponomareva A. A. Shuldyakov A. V. Anashchenko A. P. Rebrov |
| author_facet | E. Yu. Ponomareva A. A. Shuldyakov A. V. Anashchenko A. P. Rebrov |
| author_sort | E. Yu. Ponomareva |
| collection | DOAJ |
| description | The symptoms similar to those detected in rheumatic diseases in patients infected with human immunodeficiency virus (HIV) are due to various pathogenetic mechanisms (immune cell imbalance, antibody production, etc.). The occurrence of rheumatic symptoms and syndromes in HIV infection can lead to diagnostic errors and wrong treatment policy (use of immunosuppressive therapy instead of high-dose antiretroviral therapy). The paper describes two clinical cases of HIV infection in the stage of acquired immunodeficiency syndrome (AIDS) in young and middle-aged women, who were misdiagnosed rheumatic diseases at baseline. In the first case, a 34-year-old woman was suspected to have systemic lupus erythematosus before HIV infection diagnosis, whereas the leading clinical syndrome was nephropathy (nephrotic syndrome, hypertension). In the other case, in a 62-year-old woman, the manifestations of the advanced stage of HIV infection at baseline were regarded as mixed connective tissue disease, while the greatest similarity was found in the concurrence of Sjö gren’s syndrome. The paper discusses the reasons for diagnostic difficulties in each case and the specific features of organ damages in comparison with the data available in the literature. |
| format | Article |
| id | doaj-art-d02e52c3f2bc46f6ae742b4bdc8b36c7 |
| institution | Matheson Library |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2018-09-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-d02e52c3f2bc46f6ae742b4bdc8b36c72025-08-04T17:03:58ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922018-09-0156452553010.14412/1995-4484-2018-525-5302393THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASESE. Yu. Ponomareva0A. A. Shuldyakov1A. V. Anashchenko2A. P. Rebrov3V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, SaratovV.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, SaratovSaratov Regional Center for AIDS Prevention and Control, SaratovV.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, SaratovThe symptoms similar to those detected in rheumatic diseases in patients infected with human immunodeficiency virus (HIV) are due to various pathogenetic mechanisms (immune cell imbalance, antibody production, etc.). The occurrence of rheumatic symptoms and syndromes in HIV infection can lead to diagnostic errors and wrong treatment policy (use of immunosuppressive therapy instead of high-dose antiretroviral therapy). The paper describes two clinical cases of HIV infection in the stage of acquired immunodeficiency syndrome (AIDS) in young and middle-aged women, who were misdiagnosed rheumatic diseases at baseline. In the first case, a 34-year-old woman was suspected to have systemic lupus erythematosus before HIV infection diagnosis, whereas the leading clinical syndrome was nephropathy (nephrotic syndrome, hypertension). In the other case, in a 62-year-old woman, the manifestations of the advanced stage of HIV infection at baseline were regarded as mixed connective tissue disease, while the greatest similarity was found in the concurrence of Sjö gren’s syndrome. The paper discusses the reasons for diagnostic difficulties in each case and the specific features of organ damages in comparison with the data available in the literature.https://rsp.mediar-press.net/rsp/article/view/2601hiv/aidsrheumatic symptomssystemic lupus erythematosusnephropathysjö gren’s syndromediffuse infiltrative lymphocytosis |
| spellingShingle | E. Yu. Ponomareva A. A. Shuldyakov A. V. Anashchenko A. P. Rebrov THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES Научно-практическая ревматология hiv/aids rheumatic symptoms systemic lupus erythematosus nephropathy sjö gren’s syndrome diffuse infiltrative lymphocytosis |
| title | THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES |
| title_full | THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES |
| title_fullStr | THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES |
| title_full_unstemmed | THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES |
| title_short | THE CLINICAL MANIFESTATION OF HIV INFECTION SIMULATING RHEUMATIC DISEASES |
| title_sort | clinical manifestation of hiv infection simulating rheumatic diseases |
| topic | hiv/aids rheumatic symptoms systemic lupus erythematosus nephropathy sjö gren’s syndrome diffuse infiltrative lymphocytosis |
| url | https://rsp.mediar-press.net/rsp/article/view/2601 |
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