CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION

The aim of our study was to determine seroepidemiological links of Сhlamydia pneumoniae (CP), by IgA and IgG antibodies titers, with Coronary Heart Disease (CHD) in Makhachkala. A total of 122 coronary patients (average age of 54,6 ± 0,72 years) has been assessed (mean age of 54, 60, 72 years). The...

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Main Authors: Z. G. Gadjiyeva, A. S. Khasayev
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2003-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1769
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author Z. G. Gadjiyeva
A. S. Khasayev
author_facet Z. G. Gadjiyeva
A. S. Khasayev
author_sort Z. G. Gadjiyeva
collection DOAJ
description The aim of our study was to determine seroepidemiological links of Сhlamydia pneumoniae (CP), by IgA and IgG antibodies titers, with Coronary Heart Disease (CHD) in Makhachkala. A total of 122 coronary patients (average age of 54,6 ± 0,72 years) has been assessed (mean age of 54, 60, 72 years). The control group was made of 40 subjects (mean age 43,8 ± 1,28 years). Antibodies detection was made by means of solid phase immune enzyme assay. CP prevalence value in coronary patients has been found to have almost no difference from the one detected in the control group (p > 0,05). At the same time the difference in anti=CP=IgA in patients and healthy subjects was almost fourfold: 74,5% and 20,0 %, respectively (р < 0,001). A reliable difference in CP prevalence between groups of patients with stable and unstable angina was observed in IgA (p < 0,02) and in IgG (p < 0,05) as well. The data show previous CP infection and bacteria hosting not to be connected to CHD prevalence values. Only acute CP infection was associated with clinically manifest CHD.
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language Russian
publishDate 2003-08-01
publisher «FIRMA «SILICEA» LLC
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series Российский кардиологический журнал
spelling doaj-art-cfd4fb50d6a94ff2a00dc78ab98211d02025-08-04T12:59:57Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202003-08-010445481533CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATIONZ. G. Gadjiyeva0A. S. Khasayev1Дагестанская государственная медицинская академия, МахачкалаДагестанская государственная медицинская академия, МахачкалаThe aim of our study was to determine seroepidemiological links of Сhlamydia pneumoniae (CP), by IgA and IgG antibodies titers, with Coronary Heart Disease (CHD) in Makhachkala. A total of 122 coronary patients (average age of 54,6 ± 0,72 years) has been assessed (mean age of 54, 60, 72 years). The control group was made of 40 subjects (mean age 43,8 ± 1,28 years). Antibodies detection was made by means of solid phase immune enzyme assay. CP prevalence value in coronary patients has been found to have almost no difference from the one detected in the control group (p > 0,05). At the same time the difference in anti=CP=IgA in patients and healthy subjects was almost fourfold: 74,5% and 20,0 %, respectively (р < 0,001). A reliable difference in CP prevalence between groups of patients with stable and unstable angina was observed in IgA (p < 0,02) and in IgG (p < 0,05) as well. The data show previous CP infection and bacteria hosting not to be connected to CHD prevalence values. Only acute CP infection was associated with clinically manifest CHD.https://russjcardiol.elpub.ru/jour/article/view/1769chlamydia pneumoniaecoronary heart diseaseatherosclerosisunstable angina
spellingShingle Z. G. Gadjiyeva
A. S. Khasayev
CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
Российский кардиологический журнал
chlamydia pneumoniae
coronary heart disease
atherosclerosis
unstable angina
title CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
title_full CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
title_fullStr CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
title_full_unstemmed CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
title_short CHLAMYDIA PNEUMONIAE AS A FACTOR OF CORONARY HEART DISEASE DESTABILIZATION
title_sort chlamydia pneumoniae as a factor of coronary heart disease destabilization
topic chlamydia pneumoniae
coronary heart disease
atherosclerosis
unstable angina
url https://russjcardiol.elpub.ru/jour/article/view/1769
work_keys_str_mv AT zggadjiyeva chlamydiapneumoniaeasafactorofcoronaryheartdiseasedestabilization
AT askhasayev chlamydiapneumoniaeasafactorofcoronaryheartdiseasedestabilization