Mesenchymal stromal cells from people with osteoporosis are fewer, and defective in both osteogenic and adipogenic capacity

Mesenchymal stromal cells from people with osteoporosis are fewer, and defective in both osteogenic and adipogenic capacity

Aim: Osteoporosis (OP) is caused by imbalanced bone remodelling homeostasis. It is highly prevalent, especially in post-menopausal women, resulting in high risk of fracture and morbidity. Mesenchymal stromal cells (MSCs) are osteoblast progenitors, and orchestrate the function of surrounding cells i...

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Bibliographic Details
Main Authors: Féaron C. Cassidy, Ciara Shortiss, Kerry Thompson, Ana Soriano Arroquia, Colin G. Murphy, Stephen R. Kearns, William Curtin, Katarzyna Goljanek-Whysall, Timothy O’Brien, Cynthia M. Coleman
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-06-01
Series:Exploration of Musculoskeletal Diseases
Subjects:
osteoporosis
mesenchymal stromal cell
mesenchymal stem cell
bone marrow stromal cells
osteogenesis
differentiation
Online Access:https://www.explorationpub.com/uploads/Article/A100746/100746.pdf
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