Oxetanes: formation, reactivity and total syntheses of natural products

Oxetanes are 4-membered cyclic monoethers which have found important applications in medicinal chemistry as polar and metabolically stable isosteric replacements for gem-dimethyl and carbonyl groups. This work reviews possible synthetic strategies towards these strained heterocycles, covering both d...

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Bibliographic Details
Main Authors: Peter Gabko, Martin Kalník, Maroš Bella
Format: Article
Language:English
Published: Beilstein-Institut 2025-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.21.101
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