Comparison of Adenine-Induced Rat Models for Vascular Calcification in Chronic Kidney Disease

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Comparison of Adenine-Induced Rat Models for Vascular Calcification in Chronic Kidney Disease

Vascular calcification significantly contributes to cardiovascular complications and limb loss in chronic kidney disease (CKD). To establish an optimal rat model for vascular calcification, we tested varying adenine concentrations and feeding durations in Sprague–Dawley rats (n = 72), divided into s...

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Bibliographic Details
Main Authors:	Ho Won Kang, Ji Hye Kim, A Ro Yoon, Jahyung Kim, Joonhee Kim, Min Gyu Kyung, Dong Yeon Lee
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Biology
Subjects:	adenine diet chronic kidney disease comparison rat vascular calcification
Online Access:	https://www.mdpi.com/2079-7737/14/7/814
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