Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature

Gout often presents as acute arthritis but may also present with chronic joint inflammation. For the diagnosis of an acute gout attack with its typical symptoms, the differentiation towards a bacterial joint infection is critical and mandatory. The detection of intracellular uric acid crystals in th...

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Main Authors: David Kiefer, Judith Erkenberg, Juergen Braun
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-02-01
Series:Exploration of Musculoskeletal Diseases
Subjects:
Online Access:https://www.explorationpub.com/uploads/Article/A10076/10073.pdf
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author David Kiefer
Judith Erkenberg
Juergen Braun
author_facet David Kiefer
Judith Erkenberg
Juergen Braun
author_sort David Kiefer
collection DOAJ
description Gout often presents as acute arthritis but may also present with chronic joint inflammation. For the diagnosis of an acute gout attack with its typical symptoms, the differentiation towards a bacterial joint infection is critical and mandatory. The detection of intracellular uric acid crystals in the synovial fluid of affected joints is important for the initial diagnosis of gout. In the case of a chronic course with polyarticular joint involvement, the differentiation from other inflammatory rheumatic diseases such as rheumatoid arthritis (RA) can be challenging. The case presented here is of interest because the patient initially had characteristic clinical symptoms of tophaceous gout including a typical medical history—even though rheumatoid factor and anti-citrullinated protein antibodies (anti-CCP) were positive. The course of the disease and the critical evaluation of all findings also, and most interestingly, including histological results finally suggested a main diagnosis of RA.
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institution Matheson Library
issn 2836-6468
language English
publishDate 2023-02-01
publisher Open Exploration Publishing Inc.
record_format Article
series Exploration of Musculoskeletal Diseases
spelling doaj-art-cccb82b0a5864dff9c940e159cba7af22025-07-29T02:30:47ZengOpen Exploration Publishing Inc.Exploration of Musculoskeletal Diseases2836-64682023-02-011111910.37349/emd.2023.00003Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literatureDavid Kiefer0https://orcid.org/0000-0003-1602-7649Judith Erkenberg1Juergen Braun2https://orcid.org/0000-0002-9156-5095Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, 44649 Herne, GermanyRheumazentrum Ruhrgebiet, Ruhr-University Bochum, 44649 Herne, GermanyRheumazentrum Ruhrgebiet, Ruhr-University Bochum, 44649 Herne, GermanyGout often presents as acute arthritis but may also present with chronic joint inflammation. For the diagnosis of an acute gout attack with its typical symptoms, the differentiation towards a bacterial joint infection is critical and mandatory. The detection of intracellular uric acid crystals in the synovial fluid of affected joints is important for the initial diagnosis of gout. In the case of a chronic course with polyarticular joint involvement, the differentiation from other inflammatory rheumatic diseases such as rheumatoid arthritis (RA) can be challenging. The case presented here is of interest because the patient initially had characteristic clinical symptoms of tophaceous gout including a typical medical history—even though rheumatoid factor and anti-citrullinated protein antibodies (anti-CCP) were positive. The course of the disease and the critical evaluation of all findings also, and most interestingly, including histological results finally suggested a main diagnosis of RA.https://www.explorationpub.com/uploads/Article/A10076/10073.pdfarthritis uricarheumatoid arthritisrheumatoid noduletophuspolyarthritis
spellingShingle David Kiefer
Judith Erkenberg
Juergen Braun
Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
Exploration of Musculoskeletal Diseases
arthritis urica
rheumatoid arthritis
rheumatoid nodule
tophus
polyarthritis
title Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
title_full Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
title_fullStr Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
title_full_unstemmed Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
title_short Similarities and differences between gouty arthritis and rheumatoid arthritis—an interesting case with a short look into the literature
title_sort similarities and differences between gouty arthritis and rheumatoid arthritis an interesting case with a short look into the literature
topic arthritis urica
rheumatoid arthritis
rheumatoid nodule
tophus
polyarthritis
url https://www.explorationpub.com/uploads/Article/A10076/10073.pdf
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AT juditherkenberg similaritiesanddifferencesbetweengoutyarthritisandrheumatoidarthritisaninterestingcasewithashortlookintotheliterature
AT juergenbraun similaritiesanddifferencesbetweengoutyarthritisandrheumatoidarthritisaninterestingcasewithashortlookintotheliterature