Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies
Neuroendocrine tumors comprise the heterogeneous group of malignant epithelial neoplasms, the diagnosis of which is based on their histopathologic features and immunohistochemical profile. For neuroendocrine tumors of the digestive system in the World Health Organization (2010) classification were i...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-09-01
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| Series: | Успехи молекулярной онкологии |
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| Online Access: | https://umo.abvpress.ru/jour/article/view/70 |
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| author | V. V. Delektorskaya |
| author_facet | V. V. Delektorskaya |
| author_sort | V. V. Delektorskaya |
| collection | DOAJ |
| description | Neuroendocrine tumors comprise the heterogeneous group of malignant epithelial neoplasms, the diagnosis of which is based on their histopathologic features and immunohistochemical profile. For neuroendocrine tumors of the digestive system in the World Health Organization (2010) classification were introduced main categories, the nomenclature, criterions for grading and staging. However, accumulating evidence demonstrates actual controversies in the histopathology of neuroendocrine neoplasms and unreserved problems in their classification. In this review we focus on some of the common features of neuroendocrine neoplasms, their classification, and differences in pathology, biology of the main categories, and the most important immunohistochemical markers. |
| format | Article |
| id | doaj-art-cc70ea73b7ec4db1869fa2c361a19e10 |
| institution | Matheson Library |
| issn | 2313-805X 2413-3787 |
| language | Russian |
| publishDate | 2016-09-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Успехи молекулярной онкологии |
| spelling | doaj-art-cc70ea73b7ec4db1869fa2c361a19e102025-08-04T14:04:34ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872016-09-0133566610.17650/2313-805X-2016-3-3-56-6666Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversiesV. V. Delektorskaya0N. N. Blokhin Russian Cancer Reseach Center, Ministry of Health of Russia; 24 Kashirskoe Shosse, Moscow, 115478, RussiaNeuroendocrine tumors comprise the heterogeneous group of malignant epithelial neoplasms, the diagnosis of which is based on their histopathologic features and immunohistochemical profile. For neuroendocrine tumors of the digestive system in the World Health Organization (2010) classification were introduced main categories, the nomenclature, criterions for grading and staging. However, accumulating evidence demonstrates actual controversies in the histopathology of neuroendocrine neoplasms and unreserved problems in their classification. In this review we focus on some of the common features of neuroendocrine neoplasms, their classification, and differences in pathology, biology of the main categories, and the most important immunohistochemical markers.https://umo.abvpress.ru/jour/article/view/70neuroendocrine tumorgastrointestinal tractpancreaspathologyimmunohistochemical markersgradеstagе |
| spellingShingle | V. V. Delektorskaya Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies Успехи молекулярной онкологии neuroendocrine tumor gastrointestinal tract pancreas pathology immunohistochemical markers gradе stagе |
| title | Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies |
| title_full | Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies |
| title_fullStr | Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies |
| title_full_unstemmed | Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies |
| title_short | Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies |
| title_sort | morphological classification of digestive neuroendocrine neoplasms the current concepts and controversies |
| topic | neuroendocrine tumor gastrointestinal tract pancreas pathology immunohistochemical markers gradе stagе |
| url | https://umo.abvpress.ru/jour/article/view/70 |
| work_keys_str_mv | AT vvdelektorskaya morphologicalclassificationofdigestiveneuroendocrineneoplasmsthecurrentconceptsandcontroversies |