Characterization of the Biochemical Recurrence Prediction Ability and Progression Correlation of Peroxiredoxins Family in Prostate Cancer Based on Integrating Single‐Cell RNA‐Seq and Bulk RNA‐Seq Cohorts

Characterization of the Biochemical Recurrence Prediction Ability and Progression Correlation of Peroxiredoxins Family in Prostate Cancer Based on Integrating Single‐Cell RNA‐Seq and Bulk RNA‐Seq Cohorts

ABSTRACT Introduction The peroxiredoxins (PRDXs) family plays a crucial role in balancing reactive oxygen species (ROS) levels in tumor cells. However, its potential role in prognosis and therapy response of prostate cancer (PCa) remains unknown. Methods In this study, we utilized 2 public single‐ce...

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Main Authors: Shan Tang, Jinchuang Li, Weicheng Tian, Yuanfa Feng, Yulin Deng, Zeheng Tan, Zhaodong Han, Huichan He, Yongding Wu, Chuyang Huang, Keping Ning, Feng Liu, Hongwei Luo, Shanghua Cai, Jianheng Ye, Weide Zhong
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Medicine
Subjects:
biochemical recurrence
peroxiredoxins
PRDX5
prostate cancer
Online Access:https://doi.org/10.1002/cam4.70855
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