Nucleo-cytoskeletal coupling controls intracellular deformation partitioning during cell stretching

Cells sense and transduce mechanical forces to regulate diverse biological processes, yet the mechanical stimuli that initiate these processes remain poorly understood. In particular, how nuclear and cytoplasmic deformations respond to external forces is unclear. Here, we developed a microscopy-base...

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Bibliographic Details
Main Authors: Jerry Chen, Iris Sloan, Alexandra Bermudez, David Choi, Ming-Heng Tsai, Lihua Jin, Jimmy K Hu, Neil Lin
Format: Article
Language:English
Published: The Royal Society 2025-07-01
Series:Royal Society Open Science
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Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.250409
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