Inhibition of glucocorticoid-induced REDD1 expression by rapamycin in breast cancer cells

Inhibition of glucocorticoid-induced REDD1 expression by rapamycin in breast cancer cells

Introduction. Glucocorticoids are often used in combination therapy for breast cancer as an adjuvant to increase therapeutic effects of the main cytotoxic drug and to reduce side effects of chemotherapy. However, glucocorticoids can cause serious complications and trigger tumor progression. In the l...

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Bibliographic Details
Main Authors: D. D. Grigorieva, E. M. Zhidkova, E. S. Lylova, D. V. Demina, K. I. Kirsanov, G. A. Belitsky, M. G. Yakubovskaya, E. A. Lesovaya
Format: Article
Language:Russian
Published: ABV-press 2022-03-01
Series:Успехи молекулярной онкологии
Subjects:
redd1
glucocorticoids
glucocorticoid receptor
mtor inhibitors
rapamycin
sirolimus
breast cancer
Online Access:https://umo.abvpress.ru/jour/article/view/415
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