Study on the effects of spermidine on LPS-induced inflammatory osteolysis in mouse calvaria

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Study on the effects of spermidine on LPS-induced inflammatory osteolysis in mouse calvaria

Objective·To investigate the inhibitory effects of spermidine (SPD) on inflammatory osteolysis both in vivo and in vitro.Methods·The CCK-8 assay was used to assess the viability of RAW264.7 macrophages treated with various concentrations of SPD. The levels of intracellular reactive oxygen species (R...

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Bibliographic Details
Main Authors:	ZHAO Xinyu, ZHANG Wenchao, CHEN Xuzhuo, SONG Jiaqi, HUANG Hui, ZHANG Shanyong
Format:	Article
Language:	Chinese
Published:	Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2025-06-01
Series:	Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:	spermidine (spd) osteolysis osteoclast inflammation
Online Access:	https://xuebao.shsmu.edu.cn/article/2025/1674-8115/1674-8115-2025-45-6-673.shtml
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