Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis
Porphyromonas gingivalis (P. gingivalis) is considered as one of the major causes for periodontitis that eventually lead to health complications and teeth loss. In this study, crude protein extract of phycocyanin (C-PC) from Spirulina platensis that extract by precipitation and freezing/thawing met...
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| Language: | English |
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Tikrit University
2023-02-01
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| Series: | Tikrit Journal of Pure Science |
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| Online Access: | https://tjpsj.org/index.php/tjps/article/view/835 |
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| _version_ | 1839631377679515648 |
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| author | Yawooz Hameed Mahmood |
| author_facet | Yawooz Hameed Mahmood |
| author_sort | Yawooz Hameed Mahmood |
| collection | DOAJ |
| description |
Porphyromonas gingivalis (P. gingivalis) is considered as one of the major causes for periodontitis that eventually lead to health complications and teeth loss. In this study, crude protein extract of phycocyanin (C-PC) from Spirulina platensis that extract by precipitation and freezing/thawing methods, was assessed for its antimicrobial activity against its growth ATCC 33277, W50 wild type and W50 (Kgp-) W50 (Rgp-) mutant type P. gingivalis strains were used to evaluate C-PC action in the bacterial inhibition at different concentrations. The results showed that there was a decrease in ratio of the surface area for growth of bacteria has encountered in the W50 mutation strain at higher concentrations. This knowledge can be useful for the development of new oral hygienic treatments containing C-PC in the future
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| format | Article |
| id | doaj-art-ca43a1e6a1054a4cae17fbb8c668dfa8 |
| institution | Matheson Library |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-ca43a1e6a1054a4cae17fbb8c668dfa82025-07-11T16:06:07ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-02-0122710.25130/tjps.v22i7.835Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalisYawooz Hameed Mahmood Porphyromonas gingivalis (P. gingivalis) is considered as one of the major causes for periodontitis that eventually lead to health complications and teeth loss. In this study, crude protein extract of phycocyanin (C-PC) from Spirulina platensis that extract by precipitation and freezing/thawing methods, was assessed for its antimicrobial activity against its growth ATCC 33277, W50 wild type and W50 (Kgp-) W50 (Rgp-) mutant type P. gingivalis strains were used to evaluate C-PC action in the bacterial inhibition at different concentrations. The results showed that there was a decrease in ratio of the surface area for growth of bacteria has encountered in the W50 mutation strain at higher concentrations. This knowledge can be useful for the development of new oral hygienic treatments containing C-PC in the future https://tjpsj.org/index.php/tjps/article/view/835PhycocyaninantibioticPorphyromonas gingivalis |
| spellingShingle | Yawooz Hameed Mahmood Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis Tikrit Journal of Pure Science Phycocyanin antibiotic Porphyromonas gingivalis |
| title | Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis |
| title_full | Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis |
| title_fullStr | Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis |
| title_full_unstemmed | Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis |
| title_short | Evaluation the effectivness of Phycocyanin as antibiotic against Porphyromonas gingivalis |
| title_sort | evaluation the effectivness of phycocyanin as antibiotic against porphyromonas gingivalis |
| topic | Phycocyanin antibiotic Porphyromonas gingivalis |
| url | https://tjpsj.org/index.php/tjps/article/view/835 |
| work_keys_str_mv | AT yawoozhameedmahmood evaluationtheeffectivnessofphycocyaninasantibioticagainstporphyromonasgingivalis |