The broader benefits of vaccines: methodologies for inclusion in economic evaluation
Background As the societal value of vaccines is increasingly recognized, there is a need to examine methodological approaches that could be used to integrate these various benefits in the economic evaluation of a vaccine.Research design and methods A literature review and two expert panel meetings e...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Expert Review of Vaccines |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/14760584.2024.2387599 |
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| author | Steven Simoens Sandy Tubeuf Nicolas Dauby Olivier Ethgen Sophie Marbaix Marjan Willaert Jeroen Luyten |
| author_facet | Steven Simoens Sandy Tubeuf Nicolas Dauby Olivier Ethgen Sophie Marbaix Marjan Willaert Jeroen Luyten |
| author_sort | Steven Simoens |
| collection | DOAJ |
| description | Background As the societal value of vaccines is increasingly recognized, there is a need to examine methodological approaches that could be used to integrate these various benefits in the economic evaluation of a vaccine.Research design and methods A literature review and two expert panel meetings explored methodologies to value herd immunity, health spillover effects (beyond herd immunity), impact on antimicrobial resistance, productivity, and equity implications of vaccines.Results The consideration of broader benefits of vaccines in economic evaluation is complicated and necessitates technical expertise. Whereas methodologies to account for herd immunity and work productivity are relatively well established, approaches to investigate equity implications are developing and less frequently applied. Modeling the potential impact on antimicrobial resistance not only depends on the multi-faceted causal relationship between vaccination and resistance but also on data availability.Conclusions Different methods are available to value the broad impact of vaccines, and it is important that analysts are aware of their strengths and limitations and justify their choice of method. In the future, we expect that an increasing number of economic evaluations will consider the broader benefits of vaccines as part of their base-case analysis or in sensitivity analyses. |
| format | Article |
| id | doaj-art-c9fe6e49ea2f4020a02eecd9f8d0d35b |
| institution | Matheson Library |
| issn | 1476-0584 1744-8395 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Expert Review of Vaccines |
| spelling | doaj-art-c9fe6e49ea2f4020a02eecd9f8d0d35b2025-07-07T08:41:48ZengTaylor & Francis GroupExpert Review of Vaccines1476-05841744-83952024-12-0123177978810.1080/14760584.2024.2387599The broader benefits of vaccines: methodologies for inclusion in economic evaluationSteven Simoens0Sandy Tubeuf1Nicolas Dauby2Olivier Ethgen3Sophie Marbaix4Marjan Willaert5Jeroen Luyten6Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, BelgiumInstitute of Health and Society (IRSS), Université Catholique de Louvain (UClouvain), Brussels, BelgiumDepartment of Infectious Diseases, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, BelgiumDepartment of Public Health, Epidemiology and Health Economics, Faculty of Medicine, University of Liège, Liège, BelgiumResearch Institute for Health Sciences and Technology, University of Mons–UMONS, Mons, BelgiumPharma.be, Brussels, BelgiumDepartment of Public Health and Primary Care, Faculty of Medicine, KU Leuven, Leuven, BelgiumBackground As the societal value of vaccines is increasingly recognized, there is a need to examine methodological approaches that could be used to integrate these various benefits in the economic evaluation of a vaccine.Research design and methods A literature review and two expert panel meetings explored methodologies to value herd immunity, health spillover effects (beyond herd immunity), impact on antimicrobial resistance, productivity, and equity implications of vaccines.Results The consideration of broader benefits of vaccines in economic evaluation is complicated and necessitates technical expertise. Whereas methodologies to account for herd immunity and work productivity are relatively well established, approaches to investigate equity implications are developing and less frequently applied. Modeling the potential impact on antimicrobial resistance not only depends on the multi-faceted causal relationship between vaccination and resistance but also on data availability.Conclusions Different methods are available to value the broad impact of vaccines, and it is important that analysts are aware of their strengths and limitations and justify their choice of method. In the future, we expect that an increasing number of economic evaluations will consider the broader benefits of vaccines as part of their base-case analysis or in sensitivity analyses.https://www.tandfonline.com/doi/10.1080/14760584.2024.2387599Antimicrobial resistanceeconomic evaluationequityhealth spillover effectsherd immunitymethodology |
| spellingShingle | Steven Simoens Sandy Tubeuf Nicolas Dauby Olivier Ethgen Sophie Marbaix Marjan Willaert Jeroen Luyten The broader benefits of vaccines: methodologies for inclusion in economic evaluation Expert Review of Vaccines Antimicrobial resistance economic evaluation equity health spillover effects herd immunity methodology |
| title | The broader benefits of vaccines: methodologies for inclusion in economic evaluation |
| title_full | The broader benefits of vaccines: methodologies for inclusion in economic evaluation |
| title_fullStr | The broader benefits of vaccines: methodologies for inclusion in economic evaluation |
| title_full_unstemmed | The broader benefits of vaccines: methodologies for inclusion in economic evaluation |
| title_short | The broader benefits of vaccines: methodologies for inclusion in economic evaluation |
| title_sort | broader benefits of vaccines methodologies for inclusion in economic evaluation |
| topic | Antimicrobial resistance economic evaluation equity health spillover effects herd immunity methodology |
| url | https://www.tandfonline.com/doi/10.1080/14760584.2024.2387599 |
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