NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING

NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING

There was carried out the therapeutic drug monitoring of antiepileptic drug carbamazepine by use of a bayesian mathematical modeling method in 47 patients with a focal epilepsy. The database of patients pharmacokinetic characteristics concerning carbamazepine was created. According the results of ca...

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Bibliographic Details
Main Authors: Z. А. Suslina, А. K. Sariev, D. А. Аbaimov, T. YU. Noskova, R. D. Sejfulla, V. V. Shvedkov, D. I. Prokhorov, M. V. Shiryaeva, L. А. Mota
Format: Article
Language:Russian
Published: IRBIS LLC 2016-09-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
therapeutic drug monitoring (tdm)
carbamazepine
epilepsy
pharmacokinetics
a range of therapeutic concentration
computer program mm-uscpack
Online Access:https://www.epilepsia.su/jour/article/view/263
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