Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations
<b>Background:</b> Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. <b>Methods</b>: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ-Tube™ (VQ...
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MDPI AG
2025-07-01
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| author | Takho Kang Seung Gyu Yun Myung-Hyun Nam Yunjung Cho Minjeong Nam |
| author_facet | Takho Kang Seung Gyu Yun Myung-Hyun Nam Yunjung Cho Minjeong Nam |
| author_sort | Takho Kang |
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| description | <b>Background:</b> Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. <b>Methods</b>: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ-Tube™ (VQ-Tube SST), and the K<sub>2</sub>EDTA V-Tube™ (V-Tube K<sub>2</sub>EDTA) manufactured by AB Medical (Seoul, Republic of Korea), with their respective counterparts from Becton Dickinson (BD, Franklin Lakes, NJ, USA): BD Vacutainer<sup>®</sup> SST™ II Advance Tube (BD SST) and BD Vacutainer<sup>®</sup> K<sub>2</sub>EDTA 5.4 mg Tube (BD K<sub>2</sub>EDTA). The evaluation encompassed 61 measurands across the fields of chemistry, immunology, and hematology, and incorporated a stability assessment for the VQ-Tube SST. <b>Results</b>: The V-Tube SST, VQ-Tube SST, and V-Tube K<sub>2</sub>EDTA demonstrated comparable analytical performance to the BD tubes for the majority of measurands. However, glucose, lactate dehydrogenase, mean corpuscular volume, and mean corpuscular hemoglobin concentration indicated clinically significant differences according to the desirable biological variation database (Ricos). <b>Conclusions</b>: These findings suggest that, while the V-tube and VQ-tube SST generally serve as alternatives to BD tubes, caution should be taken when interpreting results for specific measurands that demonstrated clinically significant discrepancies. |
| format | Article |
| id | doaj-art-c8bc741a08a042fd8a3414f9c5bbe01d |
| institution | Matheson Library |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
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| series | Diagnostics |
| spelling | doaj-art-c8bc741a08a042fd8a3414f9c5bbe01d2025-07-25T13:19:51ZengMDPI AGDiagnostics2075-44182025-07-011514177510.3390/diagnostics15141775Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology ExaminationsTakho Kang0Seung Gyu Yun1Myung-Hyun Nam2Yunjung Cho3Minjeong Nam4Department of Laboratory Medicine, Korea University College of Medicine, Seoul 02841, Republic of KoreaDepartment of Laboratory Medicine, Korea University College of Medicine, Seoul 02841, Republic of KoreaDepartment of Laboratory Medicine, Korea University College of Medicine, Seoul 02841, Republic of KoreaDepartment of Laboratory Medicine, Korea University College of Medicine, Seoul 02841, Republic of KoreaDepartment of Laboratory Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea<b>Background:</b> Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. <b>Methods</b>: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ-Tube™ (VQ-Tube SST), and the K<sub>2</sub>EDTA V-Tube™ (V-Tube K<sub>2</sub>EDTA) manufactured by AB Medical (Seoul, Republic of Korea), with their respective counterparts from Becton Dickinson (BD, Franklin Lakes, NJ, USA): BD Vacutainer<sup>®</sup> SST™ II Advance Tube (BD SST) and BD Vacutainer<sup>®</sup> K<sub>2</sub>EDTA 5.4 mg Tube (BD K<sub>2</sub>EDTA). The evaluation encompassed 61 measurands across the fields of chemistry, immunology, and hematology, and incorporated a stability assessment for the VQ-Tube SST. <b>Results</b>: The V-Tube SST, VQ-Tube SST, and V-Tube K<sub>2</sub>EDTA demonstrated comparable analytical performance to the BD tubes for the majority of measurands. However, glucose, lactate dehydrogenase, mean corpuscular volume, and mean corpuscular hemoglobin concentration indicated clinically significant differences according to the desirable biological variation database (Ricos). <b>Conclusions</b>: These findings suggest that, while the V-tube and VQ-tube SST generally serve as alternatives to BD tubes, caution should be taken when interpreting results for specific measurands that demonstrated clinically significant discrepancies.https://www.mdpi.com/2075-4418/15/14/1775performance evaluationvacuum blood collection tubeclinical significance |
| spellingShingle | Takho Kang Seung Gyu Yun Myung-Hyun Nam Yunjung Cho Minjeong Nam Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations Diagnostics performance evaluation vacuum blood collection tube clinical significance |
| title | Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations |
| title_full | Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations |
| title_fullStr | Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations |
| title_full_unstemmed | Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations |
| title_short | Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations |
| title_sort | comparative evaluation of serum separator v tube™ vq tube™ and k sub 2 sub edta v tube™ with becton dickinson tubes for chemistry immunology and hematology examinations |
| topic | performance evaluation vacuum blood collection tube clinical significance |
| url | https://www.mdpi.com/2075-4418/15/14/1775 |
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