Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations

Comparative Evaluation of Serum Separator V-Tube™, VQ-Tube™, and K<sub>2</sub>EDTA V-Tube™ with Becton Dickinson Tubes for Chemistry, Immunology, and Hematology Examinations

<b>Background:</b> Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. <b>Methods</b>: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ-Tube™ (VQ...

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Bibliographic Details
Main Authors: Takho Kang, Seung Gyu Yun, Myung-Hyun Nam, Yunjung Cho, Minjeong Nam
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
performance evaluation
vacuum blood collection tube
clinical significance
Online Access:https://www.mdpi.com/2075-4418/15/14/1775
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Summary:<b>Background:</b> Rigorous evaluation of vacuum blood collection tubes is essential to ensure the reliability of laboratory results. <b>Methods</b>: In this study, we compared the serum separator tube V-Tube™ (V-Tube SST), the quick-clotting serum separator tube VQ-Tube™ (VQ-Tube SST), and the K<sub>2</sub>EDTA V-Tube™ (V-Tube K<sub>2</sub>EDTA) manufactured by AB Medical (Seoul, Republic of Korea), with their respective counterparts from Becton Dickinson (BD, Franklin Lakes, NJ, USA): BD Vacutainer<sup>®</sup> SST™ II Advance Tube (BD SST) and BD Vacutainer<sup>®</sup> K<sub>2</sub>EDTA 5.4 mg Tube (BD K<sub>2</sub>EDTA). The evaluation encompassed 61 measurands across the fields of chemistry, immunology, and hematology, and incorporated a stability assessment for the VQ-Tube SST. <b>Results</b>: The V-Tube SST, VQ-Tube SST, and V-Tube K<sub>2</sub>EDTA demonstrated comparable analytical performance to the BD tubes for the majority of measurands. However, glucose, lactate dehydrogenase, mean corpuscular volume, and mean corpuscular hemoglobin concentration indicated clinically significant differences according to the desirable biological variation database (Ricos). <b>Conclusions</b>: These findings suggest that, while the V-tube and VQ-tube SST generally serve as alternatives to BD tubes, caution should be taken when interpreting results for specific measurands that demonstrated clinically significant discrepancies.
ISSN:2075-4418

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